Publications associées à Insuffisance aortique

Noninvasive estimation of aortic hemodynamics and cardiac contractility using machine learning

Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia, Stamatia Zoi Pagoulatou

Cardiac and aortic characteristics are crucial for cardiovascular disease detection. However, noninvasive estimation of aortic hemodynamics and cardiac contractility is still challenging. This paper investigated the potential of estimating aortic systolic ...

2020

Acute effects of transcatheter aortic valve replacement on the ventricular-aortic interaction

Nikolaos Stergiopoulos, Georgios Rovas, Vasiliki Bikia, Stamatia Zoi Pagoulatou

Transcatheter aortic valve replacement (TAVR) is increasingly used to treat severe aortic stenosis (AS) patients. However, little is known regarding the direct effect of TAVR on the ventricular-aortic interaction. In the present study, we aimed to investig ...

AMER PHYSIOLOGICAL SOC2020

Noninvasive Cardiac Output and Central Systolic Pressure From Cuff-Pressure and Pulse Wave Velocity

Nikolaos Stergiopoulos, Bram Trachet, Vasiliki Bikia, Stamatia Zoi Pagoulatou

Goal: We introduce a novel approach to estimate cardiac output (CO) and central systolic blood pressure (cSBP) from noninvasive measurements of peripheral cuff-pressure and carotid-to-femoral pulse wave velocity (cf-PWV). Methods: The adjustment of a previ ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2020

Effect of fibre orientation and bulk modulus on the electromechanical modelling of human ventricles

Alfio Quarteroni, Antonello Gerbi, Luca Azzolin

This work concerns the mathematical and numerical modeling of the heart. The aim is to enhance the understanding of the cardiac function in both physiological and pathological conditions. Along this road, a challenge arises from the multi-scale and multi-p ...

2020

On the importance of the nonuniform aortic stiffening in the hemodynamics of physiological aging

Nikolaos Stergiopoulos, Bram Trachet, Vasiliki Bikia, Stamatia Zoi Pagoulatou

Mathematical models of the arterial tree constitute a valuable tool to investigate the hemodynamics of aging and pathology. Rendering such models as patient specific could allow for the assessment of central hemodynamic variables of clinical interest. Howe ...

AMER PHYSIOLOGICAL SOC2019

Computational fluid dynamics of blood flow in an idealized left human heart

Alfio Quarteroni, Filippo Menghini

We construct an idealized computational model of the left human heart for the study of the blood flow dynamics in the left atrium and ventricle. We solve the Navier-Stokes equations in the ALE formulation and we prescribe the left heart wall displacement b ...

WILEY2019

Nuclear receptor corepressor 1 represses cardiac hypertrophy

Johan Auwerx, Jun Wang, Chao Li, Yuan Liu, Yan Liu, Shuai Shao, Xu Liu

The function of nuclear receptor corepressor 1 (NCoR1) in cardiomyocytes is unclear, and its physiological and pathological implications are unknown. Here, we found that cardiomyocyte-specific NCoR1 knockout (CMNKO) mice manifested cardiac hypertrophy at b ...

2019

Co-localization of microstructural damage and excessive mechanical strain at aortic branches in Angiotensin-II-infused mice

Nikolaos Stergiopoulos, Lydia Aslanidou, Bram Trachet, Goran Lovric, Mauro Ferraro, Patrick Segers

Animal models of aortic aneurysm and dissection can enhance our limited understanding of the etiology of these lethal conditions particularly because early-stage longitudinal data are scant in humans. Yet, the pathogenesis of often-studied mouse models and ...

2019

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Insuffisance aortique

Noninvasive estimation of aortic hemodynamics and cardiac contractility using machine learning

Acute effects of transcatheter aortic valve replacement on the ventricular-aortic interaction

Noninvasive Cardiac Output and Central Systolic Pressure From Cuff-Pressure and Pulse Wave Velocity

Effect of fibre orientation and bulk modulus on the electromechanical modelling of human ventricles

Cardiotrophin-1 Deficiency Abrogates Atherosclerosis Progression

On the importance of the nonuniform aortic stiffening in the hemodynamics of physiological aging

Computational fluid dynamics of blood flow in an idealized left human heart

Nuclear receptor corepressor 1 represses cardiac hypertrophy

Co-localization of microstructural damage and excessive mechanical strain at aortic branches in Angiotensin-II-infused mice

The onset of cardiovascular disease in mice: an image-based, computational-experimental approach

Graph Chatbot

Chattez avec Graph Search

Noninvasive estimation of aortic hemodynamics and cardiac contractility using machine learning

Acute effects of transcatheter aortic valve replacement on the ventricular-aortic interaction

On the importance of the nonuniform aortic stiffening in the hemodynamics of physiological aging

Effect of fibre orientation and bulk modulus on the electromechanical modelling of human ventricles

Noninvasive Cardiac Output and Central Systolic Pressure From Cuff-Pressure and Pulse Wave Velocity

Cardiotrophin-1 Deficiency Abrogates Atherosclerosis Progression

Co-localization of microstructural damage and excessive mechanical strain at aortic branches in Angiotensin-II-infused mice

Computational fluid dynamics of blood flow in an idealized left human heart

Nuclear receptor corepressor 1 represses cardiac hypertrophy

The onset of cardiovascular disease in mice: an image-based, computational-experimental approach