Concept

Cyclose

Publications associées (53)

Properties of Enzymes Involved in Tetrachloroethene Respiration

Tetrachloroethene (PCE) pollution threatens nature and human health due to its toxic and carcinogenic potential. Due to industrial activities, large amounts of PCE were discharged into the environment over the last decades and represent one of major ground ...

EPFL2017

Bactericidal activity and mechanism of action of copper-sputtered flexible surfaces against multidrug-resistant pathogens

César Pulgarin, Juan Kiwi, Sami Rtimi, Myriam Koumba Sarah Ballo

Using direct current magnetron sputtering (DCMS), we generated flexible copper polyester surfaces (Cu-PES) and investigated their antimicrobial activity against a range of multidrug-resistant (MDR) pathogens including eight Gram-positive isolates (three me ...

Springer Verlag2016

A molecular chaperone dedicated to folding and translocation of reductive dehalogenases

Julien Maillard, Corantin Grob

Reductive dehalogenases (rdhA, RDases) are key enzymes involved in anaerobic organohalide respiration (OHR), during which bacteria are able to use chlorinated compounds as terminal electron acceptors. RDases are redox enzymes containing FeS clusters and a ...

2016

FOLDING OF COMPLEX REDOX PROTEINS BY DEDICATED MOLECULAR CHAPERONES

Julien Maillard, Ziad Julier, Corantin Grob

Chlorinated compounds (so-called organohalides) are widespread soil and groundwater pollutants. Only few bacteria have the ability to degrade these compounds via organohalide respiration (OHR). Reductive dehalogenases (RDases) are complex redox enzymes inv ...

2016

The DNA-Uptake Process of Naturally Competent Vibrio cholerae

Melanie Blokesch, Noémie Matthey

The sophisticated DNA-uptake machinery used during natural transformation is still poorly characterized, especially in Gram-negative bacteria where the transforming DNA has to cross two membranes as well as the peptidoglycan layer before entering into the ...

Elsevier2016

Centriolar CPAP/SAS-4 Imparts Slow Processive Microtubule Growth

Pierre Gönczy, Nicola Jane Dynes, Ashwani Sharma

Centrioles are fundamental and evolutionarily conserved microtubule-based organelles whose assembly is characterized by microtubule growth rates that are orders of magnitude slower than those of cytoplasmic microtubules. Several centriolar proteins can int ...

2016

A Spatiotemporal Characterization Method for the Dynamic Cytoskeleton

Jeremy Teo

The significant gap between quantitative and qualitative understanding of cytoskeletal function is a pressing problem; microscopy and labeling techniques have improved qualitative investigations of localized cytoskeleton behavior, whereas quantitative anal ...

Wiley-Blackwell2016

Polymer-theory insights into biomolecular systems

Salvatore Assenza

Boosted by the technological advances in experimental techniques, cellular biology is nowadays facing the need for quantitative approaches in order to rationalize the huge amount of collected data. A particularly succesfull theoretical framework is provide ...

EPFL2015

Inertial microfluidic programming of microparticle-laden flows for solution transfer around cells and particles

Patrick Alain Sandoz, Léo Hamed Amini

Control of particles/cells and the surrounding fluid is enabling toward the purification of complex cellular samples, which still remains a bottleneck for point-of-care diagnostic devices. We explore a newly developed approach to engineer fluid stream moti ...

Springer Heidelberg2015

Iron regulatory proteins and their role in controlling iron metabolism

Cellular iron homeostasis is regulated by post-transcriptional feedback mechanisms, which control the expression of proteins involved in iron uptake, release and storage. Two cytoplasmic proteins with mRNA-binding properties, iron regulatory proteins 1 and ...

Royal Soc Chemistry2015

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