Concept

Stimulant

Publications associées (35)

CO2 exchange between air and water in an Arctic Alaskan and midlatitude Swiss lake: Importance of convective mixing

[1] CO2 exchange between lake water and the atmosphere was investigated at Toolik Lake (Alaska) and Soppensee (Switzerland) employing the eddy covariance (EC) method. The results obtained from three field campaigns at the two sites indicate the importance ...

Amer Geophysical Union2003

Comparison of the effects of modafinil and sleep deprivation on sleep and cortical EEG spectra in mice

Pierre Magistretti, Jean-Marie Petit

Modafinil is a wakefulness-promoting substance whose profile differs from that of the classical psychostimulants. It is still unknown whether waking induced by modafinil and wakefulness induced by sleep deprivation differ in terms of their effect on subseq ...

2002

Neuroprotective gene therapy for Huntington's disease using a polymer encapsulated BHK cell line engineered to secrete human CNTF

Patrick Aebischer

Huntington's disease (HD) is an autosomal dominant genetic disease with devastating clinical effects on cognitive, psychological, and motor functions. These clinical symptoms primarily relate to the progressive loss of medium-spiny GABA-ergic neurons of th ...

2000

Attenuation of 6-OHDA-induced neurotoxicity in glutathione peroxidase transgenic mice

Patrick Aebischer, Jean-Charles Bensadoun

Normal cellular metabolism produces oxidants which are neutralized within cells by antioxidant enzymes and other antioxidants. An imbalance between oxidants and antioxidants has been postulated to lead to the degeneration of specific populations of neurons ...

1998

Metabolic consequences of phosphotransferase (PTS) mutation in a phenylalanine-producing recombinant Escherichia coli

Vassily Hatzimanikatis

E. coli strain PPA305, which has a wild-type PTS system, and PPA316, which utilizes a proton-galactose symport system for glucose uptake, were used as host strains to harbor a phenylalanine overprodn. plasmid pSY130-14 and to study the effects of using dif ...

1997

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