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Hematopoietic stem cells (HSCs) are responsible for life-long production of all mature blood cells. Under homeostasis, HSCs in their native bone marrow niches are believed to undergo asymmetric cell divisions (ACDs), with one daughter cell maintaining HSC ...
Everyday life physiological functions such as breathing, muscle contraction, and blood circulation rely on the ability of single cells to organize into higher complexity structures and sustain mechanical deformations. Cell monolayers are the simplest tissu ...
Ultrasound contrast agents (UCAs) have opened up immense diagnostic possibilities by combined use of indicator dilution principles and dynamic contrast-enhanced ultrasound (DCE-US) imaging. UCAs are microbubbles encapsulated in a biocompatible shell. With ...
Mitochondrial dysfunction is associated with aging-mediated inflammatory responses, leading to metabolic deterioration, development of insulin resistance, and type 2 diabetes. Growth differentiation factor 15 (GDF15) is an important mitokine generated in r ...
In this work, we report the demonstration of the capability of electrochemical sensors to provide measurements directly on the sweat of volunteers to successfully discriminate heavy smokers by light ones. Since its importance as pharmaceutical treatment-ag ...
The use of modern molecular biology tools and simple but powerful tractable model organisms such as Drosophila has contributed significantly to our recent advances in the innate immunity field, notably phagocytosis. Since 2001, many phagocytic transmembran ...
This article presents two algorithms developed based on two different techniques, from clusterization theory, namely k-means clustering technique and Fuzzy C-means technique, respectively. In this context, the study offers a sustained comparison of the two ...
Animals require complex metabolic and physiological adaptations to maintain the function of vital organs in response to environmental stresses and infection. Here, we found that infection or injury in Drosophila induced the excretion of hemolymphatic lipid ...
Optical diffraction tomography (ODT) provides us 3D refractive index (RI) distributions of transparent samples. Since RI values differ across different materials, they serve as endogenous contrasts. It, therefore, enables us to image without pre-processing ...
We study the flow properties of red blood cells in confined channels, when the channel width is comparable to the cell size. We focus on the case of intermediate concentrations when hydrodynamic interactions between cells play a dominant role. This regime ...
