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To maintain appropriate body iron levels, iron absorption by the proximal duodenum is thought to be controlled by hepcidin, a polypeptide secreted by hepatocytes in response to high serum iron. Hepcidin limits basolateral iron efflux from the duodenal epit ...
Dendritic cells (DCs) are crucial for the onset of adaptive immunity. Their outstanding migratory capacities in combination with their antigen presenting properties make them perfectly suited to pick up antigens in the periphery and transport them to the l ...
BACKGROUND & AIMS: The WNT-adenomatous polyposis coli system controls cell fate in the intestinal epithelium, where compartment-specific genes tightly regulate proliferation, migration, and differentiation. Nuclear receptors are transcription factors funct ...
Erwinia Virulence Factor (Evf) has been identified in Erwinia carotovora carotovora 15 (Ecc15) as a virulence factor that promotes colonization of the Drosophila larval gut and provokes the triggering of a systemic immune response. Here we have analysed ho ...
The present invention discloses a device (CD) for converting a first motion (x s ) into a second motion ( y) responsive to said first movement (x s ) under a demagnification scale (i), comprising: a) an input portion (IP) being drivable in a rectilinear tr ...
The Point Ahead Angle Mechanism (PAAM) for ESA’s Laser Interferometer Space Antenna (LISA) mission will compensate the out-of-plane point-ahead angle between three satellites flying 5 million kilometres apart. The PAAM consists of a mirror supported by fle ...
The peritrophic matrix (PM) forms a layer composed of chitin and glycoproteins that lines the insect intestinal lumen. This physical barrier plays a role analogous to that of mucous secretions of the vertebrate digestive tract and is thought to protect the ...
Ductal cells of the pancreas form the epithelial lining of the branched tubes that deliver enzymes produced by pancreatic acinar cells into the duodenum. In addition, these cells secrete bicarbonate that neutralizes stomach acidity. During development, epi ...
Mutations and deregulation of adenomatous polyposis coli (APC) and beta-catenin are implicated in specific cancers of the pancreas, but the role of Wnt pathway in normal pancreas development and homeostasis is unknown [1-4]. This article reports a comprehe ...
The patented Nanoconverter is as planar flexure-based structure that attenuates linear movement amplitudes by a large constant reduction factor that can be chosen by design typically between 20 and 1000. It allows using conventional commercial actuators wi ...
