Concept

Insuffisance rénale aiguë

Publications associées (64)

Assessing snow instability in skier-triggered snow slab avalanches by combining failure initiation and crack propagation

Dry-snow slab avalanches start with a local failure in a weak snowpack layer buried below cohesive snow slab layers. If the size of the failed zone exceeds a critical size, rapid crack propagation occurs possibly followed by slab release if the slope is st ...

2017

New technologies – new insights into the pathogenesis of hepatic encephalopathy

Bernard Lanz

Hepatic encephalopathy (HE) is a neuropsychiatric syndrome which frequently accompanies acute or chronic liver disease. It is characterized by a variety of symptoms of different severity such as cognitive deficits and impaired motor functions. Currently, H ...

Springer Verlag2016

Brain edema: a valid endpoint for measuring hepatic encephalopathy?

Cristina Ramona Cudalbu

Hepatic encephalopathy (HE) is a major complication of liver failure/disease which frequently develops during the progression of end-stage liver disease. This metabolic neuropsychiatric syndrome involves a spectrum of symptoms, including cognition impairme ...

Springer Verlag2016

Snow instability evaluation: calculating the skier-induced stress in a multi-layered snowpack

Johan Alexandre Philippe Gaume, Jürg Schweizer, Alec van Herwijnen

The process of dry-snow slab avalanche formation can be divided into two phases: failure initiation and crack propagation. Several approaches tried to quantify slab avalanche release probability in terms of failure initiation based on shear stress and stre ...

2016

Urine Fetuin-A is a biomarker of autosomal dominant polycystic kidney disease progression

Daniel Constam, Dmitri Firsov, Séverine Marguerite Urfer, Florian Urs Bernet

Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by numerous fluid-filled cysts that frequently result in end-stage renal disease. While promising treatment options are in advanced clinical development, early diagnos ...

BioMed Central2015

Bicaudal C1 promotes pancreatic NEUROG3+ endocrine progenitor differentiation and ductal morphogenesis

Laurence Anne E Lemaire

Mutations in Bicaudal C1 (BICC1), an RNA binding protein involved in translational regulation, have been associated with cystic kidney disease both in humans and in mice. Since kidney cysts associate with pancreatic defects in several human syndromes, we i ...

EPFL2015

Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury

Lukas Kühn

Ferritin plays a central role in iron metabolism and is made of 24 subunits of 2 types: heavy chain and light chain. The ferritin heavy chain (FtH) has ferroxidase activity that is required for iron incorporation and limiting toxicity. The purpose of this ...

American Society for Clinical Investigation2013

Multisystem Neuroprosthetic Training Improves Bladder Function After Severe Spinal Cord Injury

Grégoire Courtine, Rubia van den Brand, Daniel Eberli

Severe spinal cord injury leads to neurogenic bladder dysfunction. We recently developed a multisystem neuroprosthetic training program that promotes plastic changes capable of restoring refined locomotion in rats with severe spinal cord injury. We investi ...

Elsevier Science Inc2013

Near-Infrared 808 nm Light Boosts Complex IV-Dependent Respiration and Rescues a Parkinson-Related pink1 Model

Hubert van den Bergh, Georges Wagnières, Blaise Lovisa, Alec Ginggen

Mitochondrial electron transport chain (ETC) defects are observed in Parkinson's disease (PD) patients and in PD fly- and mouse-models; however it remains to be tested if acute improvement of ETC function alleviates PD-relevant defects. We tested the hypot ...

2013

The Effect of Valsartan versus Non-RAAS Treatment on Autoregulation of Cerebral Blood Flow

Jean-Marc Vesin

Background: Cerebral autoregulation (CA) is a protective mechanism which maintains the steadiness of the cerebral blood flow (CBF) through a broad range of systemic blood pressure (BP). Acute hypertension has been shown to reduce the cerebrovascular adapta ...

Karger2012

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