A transdiagnostic process is a proposed psychological mechanism underlying and connecting a group of mental disorders. Over the last two centuries, western mental health science has focused on nosology whereby panels of experts identify hypothetical sets of signs and symptoms, label, and compile them into taxonomies such as the Diagnostic and Statistical Manual of Mental Disorders. While this is one of the approaches that has historically driven progress in medicine, such taxonomies have long been controversial on grounds including bias, diagnostic reliability and potential conflicts of interest amongst their promoters. Over-reliance on taxonomy may have created a situation where its benefits are now outweighed by the fragmentation and constraints it has caused in the training of mental health practitioners, the range of treatments they can provide under insurance cover, and the scope of new research. To date, no biological marker or individual cognitive process has been associated with a unique mental diagnosis but rather such markers and processes seem implicated across many diagnostic categories. For these reasons, researchers have recently begun to investigate mechanisms through which environmental factors such as poverty, discrimination, loneliness, aversive parenting, and childhood trauma or maltreatment might act as causes of many disorders and which therefore might point towards interventions that could help many people affected by them. Research suggests that transdiagnostic processes may underlie multiple aspects of cognition including attention, memory/imagery, thinking, reasoning, and behavior. While an exhaustive, confirmed list of transdiagnostic processes does not yet exist, relatively strong evidence exists for processes including: Selective attention to external stimuli Selective attention to internal stimuli Avoidance behaviour: distracting ourselves or deliberately not entering feared situations, thereby blocking the opportunity to disconfirm negative beliefs.
Michael Herzog, Simona Adele Garobbio, Maya Roinishvili, Ophélie Gladys Favrod
Dimitri Nestor Alice Van De Ville, Frank Scharnowski, Yury Koush, Gwladys Rey
Dimitri Nestor Alice Van De Ville, Farnaz Delavari