Trauma- and violence-informed care (TVIC) describes a framework for working with and relating to people who have experienced negative consequences after exposure to dangerous experiences. There is no one single TVIC framework, or model, and some go by slightly different names, including Trauma Informed Care (TIC). They incorporate a number of perspectives, principles and skills. TVIC frameworks can be applied in many contexts including medicine, mental health, law, education, architecture, addiction, gender, culture, and interpersonal relationships. They can be applied by individuals and organizations. Most TVIC principles emphasize the need to understand the scope of what constitutes danger and how resulting trauma impacts human health, thoughts, feelings, behaviors, communications, and relationships. Exposure to life-altering danger necessitates a need for careful and healthy attention to creating safety within healing relationships. Client-centered and capacity-building approaches are emphasized. Most frameworks incorporate a biopsychosocial perspective, attending to the integrated effects on biology (body and brain), psychology (mind), and sociology (relationship). A basic view of trauma-informed care (TIC) involves developing a holistic appreciation of the potential effects of trauma with the goal of expanding the care-provider's empathy while creating a feeling of safety. Under this view, it is often stated that a trauma-informed approach asks not "What is wrong with you?" but rather "What happened to you?" A more expansive view includes developing an understanding of danger-response. In this view, danger is understood to be broad, include relationship dangers, and can be subjectively experienced. Danger exposure is understood to impact someone's past and present adaptive responses and information processing patterns. Harris and Fallot first articulated trauma-informed care (TIC) in 2001.