Concept
Protéine de soja
Publications associées (40)
Assessment of transferable forcefields for protein simulations attests improved description of disordered states and secondary structure propensities, and hints at multi-protein systems as the next challenge for optimization
Matteo Dal Peraro, Luciano Andres Abriata
Continuous assessment of transferable forcefields for molecular simulations is essential to identify their weaknesses and direct improvement efforts. The latest efforts focused on better describing disordered proteins while retaining proper description of ...
2021Construction of a low temperature STM and studies of large molecular systems
Several aspects in the field of molecular self assembly are addressed in this thesis. Thanks to the scanning tunnelling microscope (STM), structural, electronic and magnetic properties on surfaces can be studied down to the size of a single atom. In this t ...
EPFL2016Experimental Milestones in the Discovery of Molecular Chaperones as Polypeptide Unfolding Enzymes
Pierre Goloubinoff, Andrija Finka
Molecular chaperones control the cellular folding, assembly, unfolding, disassembly, translocation, activation, inactivation, disaggregation, and degradation of proteins. In 1989, groundbreaking experiments demonstrated that a purified chaperone can bind a ...
Annual Reviews2016Life cycle assessment of algae biodiesel and its co-products
Edgard Gnansounou, Jegannathan Kenthorai Raman
There is a need to explore alternative energy sources to meet the future energy demand in a sustainable way. Algae could be a potential feed stock for biodiesel and other co-products such as animal feed and chemicals. Life cycle assessment (LCA) of such pr ...
Elsevier2016Cryo-EM structure of aerolysin variants reveals a novel protein fold and the pore-formation process
Françoise Gisou van der Goot Grunberg, Matteo Dal Peraro, Mircea Ioan Iacovache, Nuria Cirauqui Diaz
Owing to their pathogenical role and unique ability to exist both as soluble proteins and transmembrane complexes, pore-forming toxins (PFTs) have been a focus of microbiologists and structural biologists for decades. PFTs are generally secreted as water-s ...
Nature Publishing Group2016Recapitulating De Novo Alpha-Synuclein Fibrillization in a Novel Neuronal Model of Parkinson's Disease
Athough it has been established for over 100 years that Lewy bodies (LBs) represent the major pathological hallmark of Parkinson's disease (PD), we still do not know why these fibrillar intra-neuronal inclusions of the α-Synuclein (α-Syn) protein form, and ...
EPFL2015