Publications associées à Neurosciences des systèmes

An optimized protocol for assessing changes in mouse whole-brain activity using opto-fMRI

Functional magnetic resonance imaging (fMRI) in mouse brain, paired with spatially and temporally defined manipulations, offers a powerful tool to causally explain the effect of specific neuronal activity on brain network dynamics. Here, we present an opti ...

ELSEVIER2022

Investigating cognitive ability using action-based models of structural brain networks

Enrico Amico

Recent developments in network neuroscience have highlighted the importance of developing techniques for analysing and modelling brain networks. A particularly powerful approach for studying complex neural systems is to formulate generative models that use ...

OXFORD UNIV PRESS2022

Questions and controversies in the study of time-varying functional connectivity in resting fMRI

Raphaël Pierre Liégeois, Jonathan Raël Lurie, Daniel Kessler

The brain is a complex, multiscale dynamical system composed of many interacting regions. Knowledge of the spatiotemporal organization of these interactions is critical for establishing a solid understanding of the brain's functional architecture and the r ...

MIT PRESS2020

Brain Dynamics: Global Pulse and Brain State Switching

Dimitri Nestor Alice Van De Ville

A major challenge in systems-level neuroscience is to understand the dynamic formation and succession of brain states. A new study has extracted reproducible brain states from mouse resting-state fMRI data, revealing interactions between occurrences of the ...

CELL PRESS2019

Resting brain dynamics at different timescales capture distinct aspects of human behavior

Dimitri Nestor Alice Van De Ville, Raphaël Pierre Liégeois

Linking human behavior to resting-state brain function is a central question in systems neuroscience. In particular, the functional timescales at which different types of behavioral factors are encoded remain largely unexplored. The behavioral counterparts ...

Springer2019

Multiphoton microscopy in brain imaging

Graham Knott, Bohumil Maco, Ludovico Silvestri

Brain imaging is becoming an important field in the frame of the neurophotonics in correlations with other medical ones in neuroscience studying functional and morphological aspects. In this presentation an overview on multi photon imaging of the brain wil ...

Spie-Int Soc Optical Engineering2015

Statistical models of effective connectivity in neural microcircuits

Joao Emanuel Felipe Gerhard

To appreciate how neural circuits in the brain control behaviors, we must identify how the neurons comprising the circuit are connected. Neuronal connectivity is difficult to determine experimentally, whereas neuronal activity can often be readily measured ...

EPFL2014

Extraction of network topology from multi-electrode recordings: is there a small-world effect?

Wulfram Gerstner, Joao Emanuel Felipe Gerhard

The simultaneous recording of the activity of many neurons poses challenges for multivariate data analysis. Here, we propose a general scheme of reconstruction of the functional network from spike train recordings. Effective, causal interactions are estima ...

Frontiers Research Foundation2011

Essays on individual decision making under uncertainty

Elise Le Nestour

This research project is an experimental study of decision-making in very difficult contexts resembling those encountered in financial markets. The starting point was the empirical observation that financial assets are objects of a very complex kind. Speci ...

EPFL2009

From spiking neurons to rate models: a cascade model as an approximation to spiking neuron models with refractoriness

Wulfram Gerstner

A neuron that is stimulated repeatedly by the same time-dependent stimulus exhibits slightly different spike timing at each trial. We compared the exact solution of the time-dependent firing rate for a stochastically spiking neuron model with refractorines ...

2006