Publications associées à Biodisponibilité (médecine)

Crystallization of undercooled liquid fenofibrate

Formulation of hydrophobic drugs as amorphous materials is highly advantageous as this increases their solubility in water and therefore their bioavailability. However, many drugs have a high propensity to crystallize during production and storage, limitin ...

Royal Society of Chemistry2015

Label-Free Detection of Tobramycin in Serum by Transmission-Localized Surface Plasmon Resonance

Carlotta Guiducci, Thierry Buclin, Anna Ferretti, Giulia Cappi, Fabio Mario Spiga, Laurent Décosterd, Michael Beyeler

In order to improve the efficacy and safety of treatments, drug dosage needs to be adjusted to the actual needs of each patient in a truly personalized medicine approach. Key for widespread dosage adjustment is the availability of point-of-care devices abl ...

Amer Chemical Soc2015

Bioavailability of inorganic nanoparticles to planktonic bacteria and aquatic microalgae in freshwater

Paul Bowen, Nadia Rachel Von Moos

Over the past few years, engineered nanomaterials (ENMs) have penetrated nearly every sector of modern life and their broad-scale use is steadily and rapidly increasing. The (expected) elevated levels of ENMs in the environment raise concerns with regard t ...

Royal Soc Chemistry2014

A generic strategy for pharmacological caging of growth factors for tissue engineering

Matthias Lütolf, Philipp Sebastian Lienemann, Martin Ehrbar

The caging of small molecules has revolutionized biological research by providing a means to regulate a wide range of processes. Here we report on a generic pharmacological method to cage proteins in a similar fashion. The present approach is of value in b ...

2013

New Evidence of Neuroprotection by Lactate after Transient Focal Cerebral Ischaemia: Extended Benefit after Intracerebroventricular Injection and Efficacy of Intravenous Administration

Pierre Magistretti, Ximena Castillo

Background: Lactate protects mice against the ischaemic damage resulting from transient middle cerebral artery occlusion (MCAO) when administered intracerebroventricularly at reperfusion, yielding smaller lesion sizes and a better neurological outcome 48 h ...

Karger2012

Electrochemical Detection of Anti-Breast-Cancer Agents in Human Serum by Cytochrome P450-Coated Carbon Nanotubes

Giovanni De Micheli, Sandro Carrara, Camilla Baj-Rossi

We report on the electrochemical detection of anti-cancer drugs in human serum with sensitivity values in the range of 8–925 nA/µM. Multi-walled carbon nanotubes were functionalized with three different cytochrome P450 isoforms (CYP1A2, CYP2B6, and CYP3A4) ...

2012

Multi-panel drugs detection in human serum for personalized therapy

Giovanni De Micheli, Sandro Carrara, Andrea Cavallini

This work focuses on P450 biosensors based on multiwalled carbon nanotubes (MWCNT) and different cytochrome isoforms: 3A4, 2B4, 2C9. The proposed biosensors exhibit enhanced sensitivities and decreased detection limits thanks to carbon nanotubes. The MWCNT ...

Elsevier2011

Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival

Jeffrey Alan Hubbell, Melody Swartz, Conlin O'Neil, Alice Anna Tomei, Karen Dane, Jackson Eby

By delivering immunomodulatory drugs in vivo directly to lymph nodes draining an injection site, an opportunity exists to increase drug bioavailability to local immune cells. Importantly, particles smaller than 100 nm are efficiently transported through ly ...

Elsevier2011

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Biodisponibilité (médecine)

Crystallization of undercooled liquid fenofibrate

Label-Free Detection of Tobramycin in Serum by Transmission-Localized Surface Plasmon Resonance

Bioavailability of inorganic nanoparticles to planktonic bacteria and aquatic microalgae in freshwater

A generic strategy for pharmacological caging of growth factors for tissue engineering

Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos

New Evidence of Neuroprotection by Lactate after Transient Focal Cerebral Ischaemia: Extended Benefit after Intracerebroventricular Injection and Efficacy of Intravenous Administration

Electrochemical Detection of Anti-Breast-Cancer Agents in Human Serum by Cytochrome P450-Coated Carbon Nanotubes

Effect of Humic Substance Photoalteration on Lead Bioavailability to Freshwater Microalgae

Multi-panel drugs detection in human serum for personalized therapy

Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival

Graph Chatbot

Chattez avec Graph Search

Crystallization of undercooled liquid fenofibrate

Bioavailability of inorganic nanoparticles to planktonic bacteria and aquatic microalgae in freshwater

Label-Free Detection of Tobramycin in Serum by Transmission-Localized Surface Plasmon Resonance

Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos

Effect of Humic Substance Photoalteration on Lead Bioavailability to Freshwater Microalgae

Multi-panel drugs detection in human serum for personalized therapy

Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival

A generic strategy for pharmacological caging of growth factors for tissue engineering

New Evidence of Neuroprotection by Lactate after Transient Focal Cerebral Ischaemia: Extended Benefit after Intracerebroventricular Injection and Efficacy of Intravenous Administration

Electrochemical Detection of Anti-Breast-Cancer Agents in Human Serum by Cytochrome P450-Coated Carbon Nanotubes