Publications associées à Digitale

Atrial fibrillation septal pacing: translation of modelling results

Aims: Atrial fibrillation (AF) septal pacing consists of rapid pacing from a ring of electrodes around the atrial septum, leading to local capture of both atria during AF. The present model-based study evaluated the impact of the number of stimulation elec ...

Oxford Univ Press2016

Intermittent Atrial Tachycardia Promotes Repolarization Alternans and Conduction Slowing During Rapid Rates, and Increases Susceptibility to Atrial Fibrillation in a Free-Behaving Sheep Model

Jean-Marc Vesin, Florian Jousset, Etienne Pruvot

Repolarization Alternans and Atrial Remodeling Introduction Paroxysmal atrial fibrillation (AF) may be triggered by intermittent atrial tachycardia, and ultimately lead to persistent AF. However, the mechanisms by which intermittent atrial tachycardia prom ...

Wiley-Blackwell2014

Bioluminescent sensor proteins for point-of-care therapeutic drug monitoring

Rudolf Griss

To ensure efficacy but avoid toxicity, many drugs require monitoring of their concentrations in the patient’s blood during therapy. Currently, therapeutic drug monitoring (TDM) is done in diagnostic laboratories that need trained personnel and expensive in ...

EPFL2013

Therapeutic Strategies for the Treatment of Atrial Fibrillation : New Insights from Biophysical Modeling and Signal Processing

Laurent Renaud Uldry

Atrial fibrillation is the most common cardiac rhythm disorder encountered in clinical practice, often leading to severe complications such as heart failure and stroke. This arrhythmia, increasing in prevalence with age, already affects several millions of ...

EPFL2011