Concept

Biocontainment of genetically modified organisms

Publications associées (26)

New and improved methods for integrated models of metabolism and gene expression

The beginning of the 21st century was marked by the advent of disruptive technologies, which ushered an era of groundbreaking advances in fundamental sciences, carried by the great pace at which computational capabilities spread and evolved. But the new ce ...

EPFL2021

Hemagglutinin of Influenza A, but not of Influenza B and C viruses is acylated by ZDHHC2, 8, 15 and 20

Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami, Mohamed Adbelalim Gadalla

Hemagglutinin (HA), a glycoprotein of Influenza A viruses and its proton channel M2 are site-specifically modified with fatty acids. Whereas two cysteines in the short cytoplasmic tail of HA contain only palmitate, stearate is exclusively attached to one c ...

PORTLAND PRESS LTD2020

Functional and Responsive Polymers via Controlled Radical Polymerization

Jian Wang

This Thesis is built around 4 topics, which share in common that they all take advantage of the assets of controlled radical polymerization to either (i) prepare well-defined model systems to address fundamental research questions with regard to the sensit ...

EPFL2020

Production of Algae for Biomaterials and Bioenergy: Closing the Nutrient Cycle and Enhancing the Light Utilisation Efficiency

Eya Nicodeme

Microalgae are small organisms that live in water and use solar energy or artificial light to grow. They are emerging to be one of the most promising long-term, sustainable sources of biomass for fuel, food, feed, and other high valuable co-products. Like ...

EPFL2020

Chiral fermion asymmetry in high-energy plasma simulations

The chiral magnetic effect (CME) is a quantum relativistic effect that describes the appearance of an additional electric current along a magnetic field. It is caused by an asymmetry between the number densities of left- and right-handed fermions, which ca ...

2020

Topology of Pretreated Wood Fibers Using Dynamic Nuclear Polarization

David Lyndon Emsley, Jeremy Luterbacher, Arthur César Pinon, Pierrick Berruyer, Jasmine Viger-Gravel, Wu Lan, Michel Bardet

In the continuously developing field of lignocellulosic biomass, high-yield lignin depolymerization processes are sought to optimize its productivity and profitability. Recently, formaldehyde stabilization during lignin extraction and biomass pretreatment ...

AMER CHEMICAL SOC2019

Protein Engineering Tools to Explore the Function of Protein Post-Translational Modifications for Chromatin and Microtubule Cytoskeletal Biology

Ninad Dilip Agashe

Protein post-translational modifications (PTMs) play a crucial role in expanding the protein diversity and are one of the major mechanisms through which cells respond to ever changing environmental cues. The function of two of the most important cellular c ...

EPFL2019

Quantitative single-cell analysis of S. cerevisiae using a microfluidic live-cell imaging platform

Johannes Becker

Genome-wide manipulations and measurements have made huge progress over the last decades. In Saccharomyces cerevisiae, a well-studied eukaryotic model organism, homologous recombination allows for systematic deletion or alteration of a majority of its gene ...

EPFL2015

Avoiding compositional drift during the RAFT copolymerization of N-(2-hydroxypropyl)methacrylamide and N-acryloxysuccinimide: towards uniform platforms for post-polymerization modification

Harm-Anton Klok, John Moraes, Hedi Ketari, Ioana-Maria Simionca

Controlled radical polymerization techniques such as RAFT allow fine control over polymer molecular weight and architecture. These techniques, however, do not eliminate compositional drifts in copolymerizations, which are the consequence of differences in ...

Royal Society of Chemistry2015

Alpha-synuclein Post-translational Modifications as Potential Biomarkers for Parkinson Disease and Other Synucleinopathies

Hilal Lashuel, Marc Moniatte, Bruno Claude Daniel Fauvet, Adrian Schmid

The development of novel therapies against neurodegenerative disorders requires the ability to detect their early, presymptomatic manifestations in order to enable treatment before irreversible cellular damage occurs. Precocious signs indicative of neurode ...

Amer Soc Biochemistry Molecular Biology Inc2013

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