Concept
Athérome
Publications associées (101)
Combining European and US risk prediction models with polygenic risk scores to refine cardiovascular prevention: the CoLaus|PsyCoLaus Study
Jacques Fellay, Christian Axel Wandall Thorball, Stéphane Fournier, Roxane De La Harpe
Lay Summary The aim of this study is to determine whether using polygenic risk scores improves the prediction of atherosclerotic cardiovascular disease risk when combined with clinical scores currently recommended by European and US guidelines on cardiovas ...
OXFORD UNIV PRESS2023Impact and implications of mixed plaque class in automated characterization of complex atherosclerotic lesions
Atherosclerosis is a complex disease altering vasculature morphology, and subsequently flow, with progressive plaque formation, mural disruption, and lumen occlusion. Determination of clinically-relevant plaque components-particularly calcium, lipid, and f ...
PERGAMON-ELSEVIER SCIENCE LTD2022Sub-micrometer morphology of human atherosclerotic plaque revealed by synchrotron radiation-based mu CT-A comparison with histology
Histology is a long standing and well-established gold standard for pathological characterizations. In recent years however, synchrotron radiation-based micro-computed tomography (SR mu CT) has become a tool for extending the imaging of two-dimensional thi ...
PUBLIC LIBRARY SCIENCE2022Polygenic Risk Scores for Prediction of Subclinical Coronary Artery Disease in Persons Living With HIV: The Swiss HIV Cohort Study
Jacques Fellay, Christian Axel Wandall Thorball
Background. In people living with human immunodeficiency virus (HIV) (PLWH), individual polygenic risk scores (PRSs) are associated with coronary artery disease (CAD) events. Whether PRSs are associated with subclinical CAD is unknown. Methods. In Swiss HI ...
OXFORD UNIV PRESS INC2022Considerations for analysis of endothelial shear stress and strain in FSI models of atherosclerosis
Lydia Aslanidou, Fotios Savvopoulos
Atherosclerosis is a lipid driven chronic inflammatory disease that is characterized by the formation of plaques at predilection sites. These predilection sites (side branches, curved segments, and bifurcations) have often been associated with disturbed sh ...
ELSEVIER SCI LTD2021Following spatial A beta aggregation dynamics in evolving Alzheimer's disease pathology by imaging stable isotope labeling kinetics
Anders Meibom, Stéphane Laurent Escrig, Melissa Kathleen Passarelli
beta-Amyloid (A beta) plaque formation is the major pathological hallmark of Alzheimer's disease (AD) and constitutes a potentially critical, early inducer driving AD pathogenesis as it precedes other pathological events and cognitive symptoms by decades. ...
AMER ASSOC ADVANCEMENT SCIENCE2021Predicting future myocardial infarction from angiographies with deep learning
Pascal Frossard, Emmanuel Abbé, Olivier Muller, Ortal Yona Senouf, Thabodhan Mahendiran, Stéphane Fournier, Omar Raita, David Meier, Nicolas Dayer, Farhang Aminfar
In patients with stable Coronary Artery Disease (CAD), the identification of lesions which will be responsible of a myocardial infarction (MI) during follow-up remains a daily challenge. In this work, we propose to predict culprit stenosis by applying a de ...
2021Optical Characterization of an Intra-Arterial Light and Drug Delivery System for Photodynamic Therapy of Atherosclerotic Plaque
Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Andreas Pitzschke, Manish Jain, Ying Xiao
Although the versatility of photodynamic therapy (PDT) is well established, the technical aspects of light delivery systems vary significantly depending on the targeted organ. This article describes the optical properties of a light and drug delivery syste ...
2020