Concept
Caulobacter crescentus
Publications associées (17)
Resolving bacterial cell biology: from replisome dynamics to cell wall synthesis
Bacteria are ubiquitous single cellular organisms. Compared to eukaryotic cells, bacteria have two unique characteristics: the membrane-less nucleoid and the cell wall built of peptidoglycan (PG). In most bacteria, a single circular chromosome is compacted ...
EPFL2024Chromosome organization shapes replisome dynamics in Caulobacter crescentus
Suliana Manley, Chen Zhang, Laurent Casini
DNA replication in bacteria takes place on highly compacted chromosomes, where segregation, transcription, and repair must occur simultaneously. Within this dynamic environment, colocalization of sister replisomes has been observed in many bacterial specie ...
Nature Portfolio2024Bacterial colonization in realistic environments: how mechanics impact biofilm formation in the wild and during infection
A variety of physical inputs acts onto bacteria in nature. However, these are most often ignored in the studies of their physiology. There is now increasing evidence indicating that bacteria respond to physical stimuli, including mechanical forces. Yet, qu ...
EPFL2023A ‘common garden’ to understand and predict effects of glacier shrinkage of microbial life in high-mountain streams
Tom Ian Battin, Hannes Markus Peter, Susheel Bhanu Busi, Grégoire Marie Octave Edouard Michoud, Leïla Ezzat, Tyler Joe Kohler, Jade Brandani, Stylianos Fodelianakis, Paraskevi Pramateftaki
In alpine regions worldwide, climate change has induced unprecedented glacier shrinkage, and various stream ecosystems draining glacierized catchments are experiencing profound environmental changes. However, how microbial life in these streams will be aff ...
2022Bacteria: Driving polar growth
Profiling the phenotype of 200,000 mutants revealed a new cofactor that may help a group of rod-shaped bacteria elongate and grow. ...
2020Time-lapse high-resolution microscopy to study the morphogenesis of microorganisms
Mélanie Thérèse Marie Hannebelle
Mycobacterium tuberculosis, the etiological agent for the tuberculosis disease, is a bacterial pathogen thought to infect about a quarter of the global human population. It is the first cause of death among infectious diseases, and is most prevalent in low ...
EPFL2020Bacterial cell cycle dynamics: size regulation during exponential growth and role of polyphosphate during starvation response
Bacteria are the most diverse and abundant kingdom of life and have adapted to survive and thrive in habitats around the globe. When provided with ample nutrients they grow and divide at staggering rates, increasing their population exponentially. Upon nut ...
EPFL2019Two nanomachines drive evolution in diverse Vibrio species
Horizontal gene transfer (HGT) has a major impact on bacterial evolution, leading to acquisition or deletion of genes and gene clusters, including those encoding antibiotic resistances and virulence factors. HGT therefore contributes to pathogen emergence, ...
EPFL2019Constriction Rate Modulation Can Drive Cell Size Control and Homeostasis in C. crescentus
Suliana Manley, Seamus John Holden, Anna Archetti, Aster Louis K Vanhecke, Ambroise Justin Lambert, Felix Max Schaber
Rod-shaped bacteria typically grow first via sporadic and dispersed elongation along their lateral walls and then via a combination of zonal elongation and constriction at the division site to form the poles of daughter cells. Although constriction compris ...
CELL PRESS2018