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Publications associées (63)

The HDAC inhibitor SAHA improves depressive-like behavior of CRTC1-deficient mice: Possible relevance for treatment-resistant depression

Major depression is a highly complex disabling psychiatric disorder affecting millions of people worldwide. Despite the availability of several classes of antidepressants, a substantial percentage of patients are unresponsive to these medications. A better ...

Elsevier2016

In the Mood for Vlog: Multimodal Inference in Conversational Social Video

Daniel Gatica-Perez, Dairazalia Sanchez Cortes

The prevalent “share what’s on your mind” paradigm of social media can be examined from the perspective of mood: short-term affective states revealed by the shared data. This view takes on new relevance given the emergence of conversational social video as ...

Assoc Computing Machinery2015

Influence of MCHR2 and MCHR2-AS1 Genetic Polymorphisms on Body Mass Index in Psychiatric Patients and In Population-Based Subjects with Present or Past Atypical Depression

Pierre Magistretti, Aurélie Delacrétaz

Obesity development during psychotropic treatments represents a major health issue in psychiatry. Melanin-concentrating hormone receptor 2 (MCHR2) is a central receptor involved in energy homeostasis. MCHR2 shares its promoter region with MCHR2-AS1, a long ...

Public Library of Science2015

Network-timing-dependent plasticity

Henry Markram, Eilif Benjamin Muller, Daniel Keller, Vincent Delattre

Bursts of activity in networks of neurons are thought to convey salient information and drive synaptic plasticity. Here we report that network bursts also exert a profound effect on Spike-Timing-Dependent Plasticity (STDP). In acute slices of juvenile rat ...

2015

Manganese-enhanced magnetic resonance imaging investigation of the Interferon-α model of depression in rats

Alessandro Daducci

Therapeutic effects of Interferon-α (IFN-α are known to be associated with CNS toxicity in humans, and in particular with depression symptoms. Animal models of IFN-α-induced depression (sickness behaviour) have been developed in rodents using various prepa ...

Elsevier2014

Self-regulation of inter-hemispheric visual cortex balance through real-time fMRI neurofeedback training

Dimitri Nestor Alice Van De Ville, Frank Scharnowski, Yury Koush

Recent advances in neurofeedback based on real-time functional magnetic resonance imaging (fMRI) allow for learning to control spatially localized brain activity in the range of millimeters across the entire brain. Realtime fMRI neurofeedback studies have ...

Elsevier2014

Long-term behavioral programming induced by peripuberty stress in rats is accompanied by GABAergic-related alterations in the amygdala

Maria del Carmen Sandi Perez, Stamatina Tzanoulinou, Vandana Veenit

Stress during childhood and adolescence is a risk factor for psychopathology. Alterations in γ-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the brain, have been found following stress exposure and fear experiences and are often implica ...

Public Library of Science2014

Social Defeat as an Animal Model for Depression

Fiona Hollis

Depression is one of the most disabling medical conditions in the world today, yet its etiologies remain unclear and current treatments are not wholly effective. Animal models are a powerful tool to investigate possible causes and treatments for human dise ...

Oxford Univ Press2014

Lasting Impact of Regret and Gratification on Resting Brain Activity and Its Relation to Depressive Traits

Dimitri Nestor Alice Van De Ville

Obtaining lower gains than rejected alternatives during decision making evokes feelings of regret, whereas higher gains elicit gratification. Although decision-related emotions produce lingering effects on mental state, neuroscience research has generally ...

Society for Neuroscience2014

Cortical Interneuron Loss and Symptom Heterogeneity in Huntington Disease

Doris Chau Voo Thu

Objective: The cellular basis of variable symptoms in Huntington disease (HD) is unclear. One important possibility is that degeneration of the interneurons in the cerebral cortex, which play a critical role in modulating cortical output to the basal gangl ...

Wiley-Blackwell2014

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