Concept

Substrat enzymatique

Publications associées (132)

The kinetic parameters and energy cost of the Hsp70 chaperone as a polypeptide unfoldase

Hsp70-Hsp40-NEF and possibly Hsp100 are the only known molecular chaperones that can use the energy of ATP to convert stably pre-aggregated polypeptides into natively refolded proteins. However, the kinetic parameters and ATP costs have remained elusive be ...

Nature Publishing Group2010

Two-Dimensional Polymer Formation on Surfaces: Insight into the Roles of Precursor Mobility and Reactivity

Daniele Passerone, Matthias Treier, Jinming Cai

We report on a combined scanning tunneling microscopy (STM), X-ray photoelectron spectroscopy (XPS), and density functional theory (DFT) study on the surface-assisted assembly of the hexaiodosubstituted macrocycle cyclohexa-m-phenylene (CHP) toward covalen ...

American Chemical Society2010

Fountain pen for scanning electrochemical microscopy

Hubert Girault, Andreas Stephan Lesch, Fernando Cortes Salazar, Dmitry Momotenko, Gunther Wittstock

A fountain pen probe has been developed to extend the scope of scanning electrochemical microscopy (SECM) experiments to dry surfaces. The fountain pen is fabricated by UV-photoablation of a polyethylene terephthalate (PET) film and consists on one side of ...

Royal Society of Chemistry2010

Biochemistry of Microbial Degradation of Hexachlorocyclohexane and Prospects for Bioremediation

Christof Holliger, Vishakha Raina

Lindane, the gamma-isomer of hexachlorocyclohexane (HCH), is a potent insecticide. Purified lindane or unpurified mixtures of this and alpha-, beta-, and gamma- isomers of HCH were widely used as commercial insecticides in the last half of the 20th century ...

2010

Polymer–protein conjugates: an enzymatic activity perspective

Harm-Anton Klok, Marc Gauthier

Proteins have been modified with polymers in diverse manners over the past 30 years. However, while proteins have been used to prepare many functional constructs, they are sensitive biomolecules and their bioactivity can be either positively or negatively ...

2010

Phototocatalytic Lithography of Poly(propylene sulfide) Block Copolymers: Toward High-Throughput Nanolithography for Biomolecular Arraying Applications

Jeffrey Alan Hubbell

Photocatalytic lithography (PCL) is an inexpensive, fast, and robust method of oxidizing surface chemical moieties to produce patterned substrates. This technique has utility in basic biological research as well as various biochip applications. We report o ...

2009

Porphyrin-based Photocatalytic Nanolithography A NEW FABRICATION TOOL FOR PROTEIN ARRAYS

Jeffrey Alan Hubbell

Nanoarray fabrication is a multidisciplinary endeavor encompassing materials science, chemical engineering, and biology. We formed nanoarrays via a new technique, porphyrin-based photocatalytic nanolithography. The nanoarrays, with controlled features as s ...

2009

Substrate effect on supramolecular self-assembly: from semiconductors to metals

Klaus Kern, Theresa Lutz, Giovanni Costantini, Dietmar Payer

Terephthalic acid (TPA) deposited on Si(111)-7 x 7, Si(111)-root 3 x root 3-Ag and Ag(111) has been studied as a model system to understand how much passivated semiconductor surfaces differ from semiconductor and metal surfaces in respect of supramolecular ...

2009

THE TWIN-ARGININE TRANSLOCATION PATHWAY IN THE OBLIGATE ANAEROBE DESULFITOBACTERIUM

Christof Holliger, Julien Maillard, Emmanuelle Rohrbach, Aurélie Duret

The genus Desulfitobacterium belong to the low-GC gram-positive phylogenic group and is a versatile obligate anaerobe capable of reducing very diverse terminal electron acceptors such as sulfite, nitrate, fumarate, thiosulfate, and a few polluting chlorina ...

2009

Soft Stylus Probes for Scanning Electrochemical Microscopy

Hubert Girault, Fernando Cortes Salazar, Gunther Wittstock, Anne-Laure Gassner, Mohamad Hojeij

A soft stylus microelectrode probe has been developed to carry out scanning electrochemical microscopy (SECM) of rough, tilted, and large substrates in contact mode. It is fabricated by first ablating a microchannel in a polyethylene terephthalate thin fil ...

2009

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