Publications associées à Carcinome urothélial

Identification of genes required for host-cell adhesion and antibiotic persistence of uropathogenic Escherichia coli via high-content screening

Uropathogenic Escherichia coli (UPEC) are the most common bacterial pathogens causing urinary tract infections (UTIs). Driven by the development of antibiotic resistant UPEC strains, UTIs have become a major public health issue and generate substantial hea ...

EPFL2022

Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression

Vassily Hatzimanikatis, Maria Masid Barcon, Ming Yang

Metabolic reprogramming is critical for tumor initiation and progression. However, the exact impact of specific metabolic changes on cancer progression is poorly understood. Here, we integrate multimodal analyses of primary and metastatic clonally-related ...

Nature Portfolio2022

Bladder Cancer Photodynamic Therapeutic Agent with Off-On Magnetic Resonance Imaging Enhancement

Jean-Claude Bünzli, Chen Xie

Acting as an extracellular matrix protein receptor, alpha(v)beta(3) integrin becomes an appealing target for photodynamic therapy of bladder cancer. Here, specific alpha(v)beta(3)-integrin-targeting porphyrinato-gadolinium complexes (Gd-PEG-R-n) are demons ...

WILEY2019

Versatility of Pyridoxal Phosphate as a Coating of Iron Oxide Nanoparticles

Heinrich Hofmann, Marijana Mionic Ebersold, Josefina Adriana Maria Bastiaansen, Ulrich Aschauer, Débora Bonvin

Pyridoxal 5'-phosphate (PLP) is the most important cofactor of vitamin B-6-dependent enzymes, which catalyses a wide range of essential body functions (e.g., metabolism) that could be exploited to specifically target highly metabolic cells, such as tumour ...

Mdpi Ag2017

Tubular Compressed Collagen Scaffolds for Ureteral Tissue Engineering in a Flow Bioreactor System

Jeffrey Alan Hubbell, Peter Frey, Hans Mattias Larsson, Elif Vardar, Kalitha Pinnagoda, Mouti Elodie Mouloungui

Ureteral replacement by tissue engineering might become necessary following tissue loss after excessive ureteral trauma, after retroperitoneal cancer, or even after failed reconstructive surgery. This need has driven innovation in the design of novel scaff ...

Mary Ann Liebert, Inc2015

Study of the influence of over-the-counter vitamin supplement intake on urine fluorescence to optimize cancer detection by fluorescence cystoscopy

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Carla Martoccia

Fluorescence cystoscopy (FC) efficiently enhances the detection and improves the therapeutic management of early bladder cancer. During an FC, about 150 ml of water is needed to inflate the bladder. The water is quickly diluted by urine which can be fluore ...

SPIE Society of Photo-optical Instrumentation Engineers2015

Optical spectroscopy of the bladder washout fluid to optimize fluorescence cystoscopy with Hexvix

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Blaise Lovisa, Carla Martoccia

Fluorescence cystoscopy enhances detection of early bladder cancer. Water used to inflate the bladder during the procedure rapidly contains urine, which may contain fluorochromes. This frequently degrades fluorescence images. Samples of bladder washout flu ...

SPIE Society of Photo-optical Instrumentation Engineers2014

Is There a Need for Smooth Muscle Cell Transplantation in Urethral Reconstruction?

Peter Frey

Background: Hypospadias and urethral strictures are conditions requiring additional tissue for reconstruction. Due to a limited source of tissue, autologous skin and oral mucosa are frequently used. However, long-term follow-up studies demonstrated signifi ...

Mary Ann Liebert, Inc2014

GLUT3 is induced during epithelial-mesenchymal transition and promotes tumor cell proliferation in non-small cell lung cancer

Bart Deplancke, Etienne Meylan, Petra Catalina Schwalie, Svenja Johanna Groeneveld, Jessica Christine Vazquez, Natasha Ella Samson, Mark Jonathan Masin

Alterations in glucose metabolism and epithelial-mesenchymal transition (EMT) constitute two important characteristics of carcinoma progression toward invasive cancer. Despite an extensive characterization of each of them separately, the links between EMT ...

2014

Tumor Vessel Normalization by Chloroquine Independent of Autophagy

Freddy Radtke

Chloroquine (CQ) has been evaluated as an autophagy blocker for cancer treatment, but it is unknown if it acts solely by inhibiting cancer cell autophagy. We report that CQ reduced tumor growth but improved the tumor milieu. By normalizing tumor vessel str ...

Elsevier2014