Concept

Membrane fluidity

Publications associées (149)

Hepatitis B subvirus particles display both a fluid bilayer membrane and a strong resistance to freeze drying: a study by solid-state NMR, light scattering, and cryo-electron microscopy/tomography

Hepatitis B surface antigen (HBsAg) subvirus particles produced from yeast share immunological determinants with mature viruses, which enable the use of HBsAg as a potent antigen for human vaccination. Because the intimate structure of such pseudoviral par ...

2013

Spatial SPION Localization in Liposome Membranes

Davide Demurtas, Alke Fink

Nanocarriers, including liposomes, offer great opportunities for targeted and controlled therapy. The development in this field has led to a large panel of drug delivery systems, which can be classified into 3 different nanovector generations. However, the ...

Ieee-Inst Electrical Electronics Engineers Inc2013

Membrane properties revealed by spatiotemporal response to a local inhomogeneity

Anne-Florence Raphaëlle Bitbol

We study theoretically the spatiotemporal response of a lipid membrane submitted to a local chemical change of its environment, taking into account the time-dependent profile of the reagent concentration due to diffusion in the solution above the membrane. ...

Elsevier BV2013

Activation and Spatial Organization of the Adenosine A2A Receptor in Supported Plasma Membrane Sheets

Sophie Roizard

G protein-coupled receptors (GPCRs) are ubiquitous mediators of signal transduction across cell membranes and constitute a very important class of therapeutic targets. The main mechanisms involving GPCR activation and signal transduction to the cell interi ...

EPFL2013

Exploring Neural Cell Dynamics with Digital Holographic Microscopy

Pierre Magistretti, Christian Depeursinge, Pierre Marquet

In this review, we summarize how the new concept of digital optics applied to the field of holographic microscopy has allowed the development of a reliable and flexible digital holographic quantitative phase microscopy (DH-QPM) technique at the nanoscale p ...

Annual Reviews2013

Mechanism of photocatalytic bacterial inactivation on TiO2 films involving cell-wall damage and lysis

César Pulgarin, Juan Kiwi

This article addresses the cell wall damage of Escherichia coil (from now on E. coil) by TiO2 suspensions. The dynamics of TiO2 photocatalysis by thin films layers is described. The films were characterized by FTIR spectroscopy and atomic force microscopy ...

Elsevier2012

Multicolor Single Molecule Tracking of Stochastically Active Synthetic Dyes

Suliana Manley, Aleksandr Benke

Single particle tracking can reveal dynamic information at the scale of single molecules in living cells but thus far has been limited either in the range of potential protein targets or in the quality and number of tracks attainable. We demonstrate a new ...

American Chemical Society2012

Spontaneous Vesicle Self-Assembly: A Mesoscopic View of Membrane Dynamics

Amphiphilic vesicles are ubiquitous in living cells and industrially interesting as drug delivery vehicles. Vesicle self-assembly proceeds rapidly from nanometer to micrometer length scales and is too fast to image experimentally but too slow for molecular ...

American Chemical Society2012

Identification of in vitro HSC fate regulators by differential lipid raft clustering

Matthias Lütolf, Alessandra Griffa, Olaia Maria Naveiras Torres-Quiroga, Aline Roch, Stefan Kobel, Nicola Vannini

Most hematopoietic stem cells (HSC) in the bone marrow reside in a quiescent state and occasionally enter the cell cycle upon cytokine-induced activation. Although the mechanisms regulating HSC quiescence and activation remain poorly defined, recent studie ...

2012

Spatially-Resolved Eigenmode Decomposition of Red Blood Cells Membrane Fluctuations Questions the Role of ATP in Flickering

Pierre Magistretti, Dimitri Nestor Alice Van De Ville, Christian Depeursinge, Benjamin Rappaz, Pierre Marquet, Daniel Boss, Annick Hoffmann

Red blood cells (RBCs) present unique reversible shape deformability, essential for both function and survival, resulting notably in cell membrane fluctuations (CMF). These CMF have been subject of many studies in order to obtain a better understanding of ...

Public Library Science2012

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