Concept

Relation gène pour gène

Publications associées (33)

Methylation of arsenic by single-species and soil-derived microbial cultures

Arsenic (As) is simultaneously a ubiquitous and a toxic element. Arsenic is subject to bio-transformations catalyzed by microorganisms constituting the As biogeochemical cycle. The primordial Earth was devoid of oxygen, exposing life to the highly mobile a ...

EPFL2020

High amounts of antibiotic resistance genes and Class I integrons are disseminated in rivers of the Mekong delta (Viet Nam) from the effluents of intensive shrimp farms

Pierre Rossi, Florian Frédéric Vincent Breider, Emmanuelle Rohrbach

In the Mekong delta, intensive shrimp farming rely heavily on a wide panel of antibiotics (ABs) to prevent disease epidemics. Consequently, large amounts of antibiotic multi-resistant bacteria are emerging, threatening adjacent aquatic habitats used for ir ...

2019

EspL is essential for virulence and stabilizes EspE, EspF and EspH levels in Mycobacterium tuberculosis

Stewart Cole, Nina Theres Odermatt, Claudia Sala, Andrej Benjak, Paloma Julia Soler Arnedo, Sofia Ulrika Magnusdotter Von Schultz

The ESX-1, type VII, secretion system represents the major virulence determinant of Mycobacterium tuberculosis, one of the most successful intracellular pathogens. Here, by combining genetic and high-throughput approaches, we show that EspL, a protein of 1 ...

PUBLIC LIBRARY SCIENCE2018

Evolution of longevity improves immunity in Drosophila

Bruno Lemaitre

Much has been learned about the genetics of aging from studies in model organisms, but still little is known about naturally occurring alleles that contribute to variation in longevity. For example, analysis of mutants and transgenes has identified insulin ...

JOHN WILEY & SONS LTD2018

Inactivation of Antibiotic Resistant Bacteria and Resistance Genes by Ozone: From Laboratory Experiments to Full-Scale Wastewater Treatment

Urs von Gunten, Nadine Czekalski, Helmut Bürgmann

Ozone, a strong oxidant and disinfectant, seems ideal to cope with future challenges of water treatment, such as micropollutants, multiresistant bacteria (MRB) and even intracellular antibiotic resistance genes (ARG), but information on the latter is scarc ...

American Chemical Society2016

Competence-induced type VI secretion might foster intestinal colonization by Vibrio cholerae

Melanie Blokesch

The human pathogen Vibrio cholerae exhibits two distinct lifestyles: one in the aquatic environment where it often associates with chitinous surfaces and the other as the causative agent of the disease cholera. While much of the research on V. cholerae has ...

Wiley-Blackwell2015

An intracellular replication niche for Vibrio cholerae in the amoeba Acanthamoeba castellanii

Melanie Blokesch, Catherine Maclachlan, Tiziana Scrignari, Charles Ulric V Van der Henst

Vibrio cholerae is a human pathogen and the causative agent of cholera. The persistence of this bacterium in aquatic environments is a key epidemiological concern, as cholera is transmitted through contaminated water. Predatory protists, such as amoebae, a ...

Nature Publishing Group2015

The PhoP-Dependent ncRNA Mcr7 Modulates the TAT Secretion System in Mycobacterium tuberculosis

Stewart Cole, Jacques Rougemont, Claudia Sala, Andrej Benjak, Swapna Uplekar

The PhoPR two-component system is essential for virulence in Mycobacterium tuberculosis where it controls expression of approximately 2% of the genes, including those for the ESX-1 secretion apparatus, a major virulence determinant. Mutations in phoP lead ...

Public Library of Science2014

Adaptive Response of Group B Streptococcus to High Glucose Conditions: New Insights on the CovRS Regulation Network

Isabella Santi

Although the contribution of carbohydrate catabolism to bacterial colonization and infection is well recognized, the transcriptional changes during these processes are still unknown. In this study, we have performed comparative global gene expression analy ...

Public Library of Science2013

Sources, Spreading and Fate of Antibiotic Resistance Genes and Resistant Bacteria in Vidy Bay, Lake Geneva, Switzerland

Nadine Czekalski

Increasing numbers of multiresistant bacterial pathogens cause severe health problems on a global scale. Large quantities of bacteria and their resistance genes are discharged into natural environments via human and animal waste. Not much is known so far a ...

EPFL2013

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