Concept

Lichen plan

Publications associées (15)

Yeast Nanometric Scale Oscillations Highlights Fibronectin Induced Changes in C. albicans

Giovanni Dietler, Sandor Kasas, Anne-Céline Verenna Kohler, Leonardo Venturelli

Yeast resistance to antifungal drugs is a major public health issue. Fungal adhesion onto the host mucosal surface is still a partially unknown phenomenon that is modulated by several actors among which fibronectin plays an important role. Targeting the ye ...

2020

Intraductal patient-derived xenografts of estrogen receptor α-positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions

Cathrin Brisken, Georgios Sflomos, Ayyakkannu Ayyanan, Laura Battista, Maryse Fiche, Valentina Scabia, Patrik Aouad, Valérian Charles Robert Dormoy

Estrogen receptor α-positive (ER-positive) or 'luminal' breast cancers were notoriously difficult to establish as patient-derived xenografts (PDXs). We and others recently demonstrated that the microenvironment is critical for ER-positive tumor cells; when ...

2018

Phenotypic Heterogeneity in Mycobacterium tuberculosis

John McKinney, Neeraj Dhar, Giulia Manina

The interaction between the host and the pathogen is extremely complex and is affected by anatomical, physiological, and immunological diversity in the microenvironments, leading to phenotypic diversity of the pathogen. Phenotypic heterogeneity, defined as ...

Amer Soc Microbiology2016

Toward the sustainable cultivation of microalgae to produce renewable biofuels and fine chemicals

Jean-Paul Schwitzguebel

Microalgae are considered as renewable feedstock for the production of next-generation biofuels. However to achieve the financial sustainability to the algal biofuel production, it will be necessary to integrate it with the processing of high-value product ...

2014

Microalgae for wastewater treatment, CO2 mitigation and biofuels : dream or sustainable maid for all work?

Christof Holliger, Jean-Paul Schwitzguebel, Eduardo Pereira Gomes, Stephen Mackay

Over the last decade, intensive research has been carried out all over the world to explore the huge potential of microalgae for biofuel production, which could be coupled to the use of industrial flue gas to enhance CO2 fixation as a greenhouse gas mitiga ...

2014

Frequent disruption of the RB pathway in indolent follicular lymphoma suggests a new combination therapy

Elisa Oricchio, Giovanni Ciriello

Loss of cell cycle controls is a hallmark of cancer and has a well-established role in aggressive B cell malignancies. However, the role of such lesions in indolent follicular lymphoma (FL) is unclear and individual lesions have been observed with low freq ...

2014

Pelletization of micro-algae by induced lichen formation through co-culture with filamentous fungi

Christof Holliger, Pierre Rossi, Jean-Paul Schwitzguebel, Eduardo Pereira Gomes, Stephen Mackay

The use of micro-algae within industrial applications, such as biofuel production, has several limitations with regard to cost and therefore sustainability. Micro-algae biomass consists of small single cells that stay in suspension making them difficult to ...

2013

Pattern Dystrophy With High Intrafamilial Variability Associated With Y141C Mutation In The Peripherin/Rds Gene And Successful Treatment Of Subfoveal Cnv Related To Multifocal Pattern Type With Anti-Vegf (Ranibizumab) Intravitreal Injections

Objective: To identify disease causing mutation in three generations of a Swiss family with pattern dystrophy and high intrafamilial variability of phenotype. To assess the effect of intravitreal ranibizumab injections in the treatment of subfoveal choroid ...

Lippincott Williams & Wilkins2012

The Role of LEKTI in the Fate Determination of Keratinocyte Stem Cells

Alessandro Wataru Amici

SPINK5 (serine protease inhibitor Kazal-type 5) encodes the proteinase inhibitor LEKTI (lympho-epithelial Kazal-type related inhibitor). In skin, LEKTI expression is restricted to the stratum granulosum of the epidermis and the inner root sheath of hair fo ...

EPFL2011

PPS nanoparticles as versatile delivery system to induce systemic and broad mucosal immunity after intranasal administration

Eleonora Simeoni, Jeffrey Alan Hubbell, Melody Swartz, Mikaël Martino, Armando Stano

Degradable polymer nanoparticles (NPs, 50nm) based on polypropylene sulfide (PPS) were conjugated to thiolated antigen and adjuvant proteins by reversible disulfide bonds and evaluated in mucosal vaccination. Ovalbumin was used as a model antigen, and anti ...

Elsevier2011

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