Concept

Théorie du cerveau triunique

Publications associées (43)

Properties of neocortical microcircuits

The mammalian neocortex is one of the most complex brain areas, integrating all sensory modalities and allowing the animal to perform high level cognitive operations. Despite some cytoarchitectural specializations, the general neocortical structure is rema ...

EPFL2009

Frequency-dependent disynaptic inhibition in the pyramidal network: a ubiquitous pathway in the developing rat neocortex

Henry Markram, Rodrigo de Campos Perin, Thomas Berger, Gilad Silberberg

The general structure of the mammalian neocortex is remarkably similar across different cortical areas. Despite certain cytoarchitectural specializations and deviations from the general blueprint, the principal organization of the neocortex is relatively u ...

2009

Genes, Brain Development and Psychiatric Phenotypes in Velo-Cardio-Facial Syndrome

Marie Schaer

Velo-cardio-facial syndrome (VCFS) has been in the focus of intensive research over the last 15 years. The syndrome represents a homogeneous model for studying the effect of a decreased dosage of genes on the development of brain structure and function and ...

2008

Inferring connection proximity in networks of electrically coupled cells by subthreshold frequency response analysis

Henry Markram, Thomas Berger, Michele Giugliano, Corrado Cali, Michele Pignatelli

Electrical synapses continuously transfer signals bi-directionally from one cell to another, directly or indirectly via intermediate cells. Electrical synapses are common in many brain structures such as the inferior olive, the subcoeruleus nucleus and the ...

Springer US2008

Molecular heterogeneity of the ganglionic eminence and its relationship to the birth of neocortical interneurons

Susan Willi Monnerat

Neocortical function and malfunction depends critically on a spectrum of inhibitory interneurons. To gain novel insight in normal brain function and mechanisms leading to diseases, such as epilepsy or schizophrenia, the knowledge about the specific functio ...

EPFL2007

Layer- and column-specific knockout of NMDA receptors in pyramidal neurons of the mouse barrel cortex

Carl Petersen, Rachel Aronoff

Viral vectors injected into the mouse brain offer the possibility for localized genetic modifications in a highly controlled manner. Lentivector injection into mouse neocortex transduces cells within a diameter of approximately 200mum, which closely matche ...

Frontiers Research Foundation2007

A Cross Validation Study of STN targeting on MRI: from Stereotactic Procedures and Automatic Registration Algorithms to direct identification

Jean-Philippe Thiran, Reto Meuli, Francisco Javier Sanchez Castro

Subthalamic nucleus (STN) Deep brain stimulation (DBS) has demonstrated its efficacy in the treatment of Parkinson´s disease. Accurate targeting of the STN is a crucial step for the success of DBS surgery. MRI has shown to be reliable and allows direct tar ...

IEEE2006

Segmentation of Brain Structures in Presence of a Space-Occupying Lesion

Jean-Philippe Thiran, Meritxell Bach Cuadra, Olivier Cuisenaire

Brain deformations induced by space-occupying lesions may result in unpredictable position and shape of functionally important brain structures. The aim of this study is to propose a method for segmentation of brain structures by deformation of a segmented ...

2005

Cortical involvement in the generation of "involuntary" movements in restless legs syndrome

Friedhelm Christoph Hummel

The pathophysiology of the restless legs syndrome (RLS) is poorly understood. One index symptom is the urge to move, increasing at night. It is largely accepted that movement in RLS is "involuntary" and that the generators are below the level of the neocor ...

2004

A connectionist model of spatial learning in the rat

Thomas Strösslin

When animals explore an environment, they store useful spatial information in their brains. In subsequent visits, they can recall this information and thus avoid dangerous places or find again a food location. This ability, which may be crucial for the ani ...

EPFL2004

Graph Chatbot

Chattez avec Graph Search

Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.

AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.

Connectez-vous pour utiliser Chat avec Graph Search