Publications associées à Motif de répétition

Control and Characterization of the Compactness of Single-Chain Nanoparticles

Francesco Stellacci, Luciano Andres Abriata, Lixia Wei, Suiyang Liao

Polymers when self-cross-linked into single-chain nanoparticles bear some resemblance to folded proteins; yet proteins have clear energy landscapes that determine precisely folded structures, while single-chain polymer nanoparticles (SCNPs) have more undef ...

American Chemical Society2021

Coincidence imaging spectroscopy of extreme-ultraviolet photoionisation processes in molecules and clusters

Andrew Daniel Bonnar Clark

Presented here is the design, construction and commissioning of a coincidence imaging spectroscopy endstation coupled to the Harmonium high-harmonic generation (HHG) extreme-ultraviolet photon source at the Lausanne Centre for Ultrafast Science. The endsta ...

EPFL2021

Architecture of the centriole cartwheel‐containing region revealed by cryo‐electron tomography

Henning Paul-Julius Stahlberg, Paul Guichard, Virginie Hamel

Centrioles are evolutionarily conserved barrels of microtubule triplets that form the core of the centrosome and the base of the cilium. While the crucial role of the proximal region in centriole biogenesis has been well documented, its native architecture ...

2020

Crosslinking Allosteric Sites on the Nucleosome Core Particle

Lucinda Kate Batchelor

Designing compounds that bind to the acidic patch of the nucleosome core particle (NCP) is an emerging therapeutic approach that can inhibit the binding of key chromatin factors. Pretreatment of human ovarian carcinoma, A2780, cells with RAPTA-T, an antime ...

EPFL2019

Histidine Targeting Heterobimetallic Ruthenium(II)-Gold(I) Complexes

Paul Joseph Dyson, Daniel Ortiz Trujillo, Lucinda Kate Batchelor

Inspired by the preferential, allosteric binding of RAPTA-T and auranofin to the nucleosome core particle, we describe the design and synthesis of a series of heterobimetallic ruthenium(II)-gold(I) complexes with varying spacer lengths ranging from four to ...

2019

The Structure of the Protonated Serine Octamer

Ursula Röthlisberger, Thomas Rizzo, Stephan Warnke, Marta Andreia Da Silva Perez, Valeriu Scutelnic, Aurelien Stephen Arnaud Gregor, Carsten Baldauf

The amino acid serine has long been known to form a protonated “magic-number” cluster containing eight monomer units that shows an unusually high abundance in mass spectra and has a remarkable homochiral preference. Despite many experimental and theoretica ...

2018

A facile synthetic strategy to polysiloxanes containing sulfonyl side groups with high dielectric permittivity

The chemical modification of polymers with lateral polar groups increases their dielectric permittivity above the glass transition temperature, making them attractive materials for dielectric elastomer actuators. Despite the large dipole moment of the sulf ...

Royal Society of Chemistry2017

High Permittivity Silicones for Dielectric Elastomer Actuators

Simon Johannes Dünki

Many technical advances of modern society sprout from the creation of specially customized polymer materials exhibiting unique combinations of properties uncharted so far. Amid this plurality of highly versatile materials, the class of electroactive polyme ...

EPFL2017

Surface Grafted Polymer Brushes : A Versatile Platform for Antibacterial Applications

Sorin Alexandru Ibanescu

Various strategies have been proposed and applied to prepare antibacterial materials able to respond to different requirements specific for antibacterial applications. Among diverse strategies the approach based on substrates modification with polymer brus ...

EPFL2015

Cyanine dye polyelectrolytes for organic bilayer solar cells

Roland Hany, Lei Wang, Hui Zhang

Polyelectrolytes composed of an anionic sulfoethyl methacrylate/methacrylate backbone and cationic cyanine dyes counter ions are synthesized. The effective reaction sequence is confirmed by NMR spectroscopy and consists of a thermal radical copolymerizatio ...

Elsevier Sci Ltd2014