Concept

Cortex entorhinal

Publications associées (154)

Expression of FGF-2 in neural progenitor cells enhances their potential for cellular brain repair in the rodent cortex

Didier Trono, Marc-Olivier Sauvain, Michiko Kanemitsu

Strategies to enhance the capacity of grafted stem/progenitors cells to generate multipotential, proliferative and migrating pools of cells in the postnatal brain could be crucial for structural repair after brain damage. We investigated whether the over-e ...

Oxford University Press2007

Dissociation of sustained attention from central executive functions: local activity and interregional connectivity in the theta range

Friedhelm Christoph Hummel

Human brain oscillatory activity was analysed in the electroencephalographic theta frequency range (4-7 Hz) while subjects executed complex sequential finger movements with varying task difficulty and memory load. Local frontal-midline theta activity was a ...

Wiley-Blackwell2007

Induction of tau pathology by intracerebral infusion of amyloid-beta-containing brain extract and by amyloid-beta deposition in APP x tau transgenic mice

Tristan Bolmont

Alzheimer's disease presents morphologically with senile plaques, primarily made of extracellular amyloid-beta (A beta) deposits, and neurofibrillary lesions, which consist of intracellular aggregates of hyper-phosphorylated tau protein. To study the in vi ...

American Society for Investigative Pathology2007

Coupling of cortical dynein and Galpha proteins mediates spindle positioning in Caenorhabditis elegans

Pierre Gönczy

Despite being essential for spatial cell division control, the mechanisms governing spindle positioning remain incompletely understood. In the Caenorhabditis elegans one-cell stage embryo, the spindle becomes asymmetrically positioned during anaphase throu ...

2007

Hippocampal volume reduction in 22q11.2 deletion syndrome

Marie Schaer

Hippocampal volume reduction and decreased memory skills form a characteristic neurofunctional alteration observed in schizophrenia. Individuals affected with 22q11.2 deletion syndrome (22q11DS), while exhibiting memory deficits throughout development, are ...

2006

Heterogeneity in the pyramidal network of the medial prefrontal cortex

Henry Markram, Thomas Berger, Yi Wang

The prefrontal cortex is specially adapted to generate persistent activity that outlasts stimuli and is resistant to distractors, presumed to be the basis of working memory. The pyramidal network that supports this activity is unknown. Multineuron patch-cl ...

2006

Mid-life stress and cognitive deficits during early aging in rats: individual differences and hippocampal correlates

Maria del Carmen Sandi Perez

We explored here the possibility that mid-life stress in rats could have deleterious effects on cognitive abilities during early aging, as well as the potential role of inter-individual differences on the development of such effects. Male Wistar rats were ...

2006

Regional and cellular gene expression changes in human Huntington's disease brain

Darlene Goldstein, Mauro Delorenzi, Doris Chau Voo Thu, Thierry Sengstag

Huntington's disease (HD) pathology is well understood at a histological level but a comprehensive molecular analysis of the effect of the disease in the human brain has not previously been available. To elucidate the molecular phenotype of HD on a genome- ...

Oxford University Press2006

Chronic restraint stress induces changes in synapse morphology in stratum lacunosum-moleculare CA1 rat hippocampus: a stereological and three-dimensional ultrastructural study

Maria del Carmen Sandi Perez, Maria Isabel Cordero Campana

Chronic restraint stress is known to affect the morphology and synaptic organization of the hippocampus, predominantly within CA3 but also in CA1 and dentate gyrus. In this study, we provide the first evidence for specific ultrastructural alterations affec ...

2006

Decreased anterior cingulate volume in combat-related PTSD

Marie Schaer

Background Neuroanatomical data point to functional relationships between the anterior cingulate cortex (ACC) and subcortical centers regulating fear, in particular, the amygdala. Functional brain imaging has disclosed divergent patterns of ACC activation ...

2006

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