Publications associées à Variation naturelle

Waterborne Virus Transport and Risk Assessment in Lake Geneva Under Climate Change

Climate changes influence lake hydrodynamics and radiation levels and thus may affect the fate and transport of waterborne pathogens in lakes. This study examines the impact of climate change on the fate, transport, and associated risks of four waterborne ...

2024

Decision support methodology for waste-to-value process integration

Rafael Amorim Leandro De Castro Amoedo

Waste treatment is a complex procedure that comprises multidimensional aspects. The challenges posed by the energy transition and international protocols emphasize the role of waste in its material and energy dimension. With an increasing population and li ...

EPFL2023

Distributed Lossy Computation with Structured Codes: From Discrete to Continuous Sources

Michael Christoph Gastpar, Sung Hoon Lim, Adriano Pastore, Chen Feng

This paper considers the problem of distributed lossy compression where the goal is to recover one or more linear combinations of the sources at the decoder, subject to distortion constraints. For certain configurations, it is known that codes with algebra ...

2023

Impact of population size on early adaptation in rugged fitness landscapes

Anne-Florence Raphaëlle Bitbol, Richard Marie Servajean

Owing to stochastic fluctuations arising from finite population size, known as genetic drift, the ability of a population to explore a rugged fitness landscape depends on its size. In the weak mutation regime, while the mean steady-state fitness increases ...

ROYAL SOC2023

The end of urban sprawl? Internal migration across the rural-urban continuum in Switzerland, 1966-2018

Mathias Lerch

In high-income countries, migration redistributed populations from congested city centres into the sparsely populated outskirts, raising challenges to environmental and population health and the conservation of biodiversity. We evaluate whether this periur ...

2023

Shannon Bounds on Lossy Gray-Wyner Networks

Michael Christoph Gastpar, Erixhen Sula

The Gray-Wyner network subject to a fidelity criterion is studied. Upper and lower bounds for the trade-offs between the private sum-rate and the common rate are obtained for arbitrary sources subject to mean-squared error distortion. The bounds meet exact ...

2022

A birth-death-migration model for life in astrophysical environments

Claudio Grimaldi

To assess the number of life-bearing worlds in astrophysical environments, it is necessary to take the intertwined processes of abiogenesis (birth), extinction (death), and transfer of life (migration) into account. We construct a mathematical model that i ...

OXFORD UNIV PRESS2021

Investigating Crosstalk Among PTMs Provides Novel Insight Into the Structural Basis Underlying the Differential Effects of Nt17 PTMs on Mutant Httex1 Aggregation

Hilal Lashuel, Matteo Dal Peraro, Luciano Andres Abriata, Lucien Fabrice Krapp, Anass Chiki, Driss Boudeffa, Iman Rostami, Rajasekhar Kolla, Zhidian Zhang

Post-translational modifications (PTMs) within the first 17 amino acids (Nt17) of the Huntingtin protein (Htt) have been shown to inhibit the aggregation and attenuate the toxicity of mutant Htt proteins in vitro and in various models of Huntington’s disea ...

2021

International Migration And The Growth Of Zurich, 1836-1949

Mathias Lerch

The role played by international migration and its interactions with other demographic components in the process of city growth remains underappreciated. We analyze trends in natural increase and in net internal and international migration in Zurich during ...

2021

Pressure on obstacles induced by granular snow avalanches

Michael Lukas Kyburz

The increasing population and the consequential demand for dwelling and recreation areas lead to more frequent conflicts between humans and natural hazards. In mountainous regions snow avalanches are, therefore, still a major threat to humans and infrastru ...

EPFL2021