Concept

Cognitive impairment

Publications associées (86)

Long-term effects of early treatment with SSRIs on cognition and brain development in individuals with 22q11.2 deletion syndrome

Maude Schneider, Marie Schaer, Karin Bortolin

Cognitive deficits in individuals at risk of psychosis represent a significant challenge for research, as current strategies for symptomatic treatment are often ineffective. Recent studies showed that atypical cognitive development predicts the occurrence ...

SPRINGERNATURE2021

Robot-induced hallucinations in Parkinson’s disease depend on altered sensorimotor processing in fronto-temporal network

Dimitri Nestor Alice Van De Ville, Olaf Blanke, Fosco Bernasconi, Jevita Potheegadoo, Michel Akselrod, Nathan Quentin Faivre, Giulio Rognini, Masayuki Hara, Michela Bassolino, Eva Blondiaux, Giedre Stripeikyte, Matteo Franza, Stéphanie Konik

Hallucinations in Parkinson’s disease (PD) are disturbing and frequent non-motor symptoms and constitute a major risk factor for psychosis and dementia. We report a robotics-based approach applying conflicting sensorimotor stimulation, enabling the inducti ...

2021

Late Fusion of the Available Lexicon and Raw Waveform-based Acoustic Modeling for Depression and Dementia Recognition

Petr Motlicek, Mathew Magimai Doss, Julian David Fritsch, Subrahmanya Pavankumar Dubagunta

Mental disorders, e.g. depression and dementia, are categorized as priority conditions according to the World Health Organization (WHO). When diagnosing, psychologists employ structured questionnaires/interviews, and different cognitive tests. Although acc ...

ISCA-INT SPEECH COMMUNICATION ASSOC2021

Dysmaturation Observed as Altered Hippocampal Functional Connectivity at Rest Is Associated With the Emergence of Positive Psychotic Symptoms in Patients With 22q11 Deletion Syndrome

Dimitri Nestor Alice Van De Ville, Maude Schneider, Farnaz Delavari, Daniela Maria Zöller, Karin Bortolin

BACKGROUND: Hippocampal alterations are among the most replicated neuroimaging findings across the psychosis spectrum. Moreover, there is strong translational evidence that preserving the maturation of hippocampal networks in mice models prevents the progr ...

ELSEVIER SCIENCE INC2021

Clinical connectome fingerprints of cognitive decline

Enrico Amico, Emahnuel Troisi Lopez

Brain connectome fingerprinting is rapidly rising as a novel influential field in brain network analysis. Yet, it is still unclear whether connectivity fingerprints could be effectively used for mapping and predicting disease progression from human brain d ...

2021

Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments

Graham Knott, Corrado Cali, Nicole Déglon, Tamara Zehnder, Luca Pucci, Andrea Chicca

Astrocytes orchestrate neural development by powerfully coordinating synapse formation and function and, as such, may be critically involved in the pathogenesis of neurodevelopmental abnormalities and cognitive deficits commonly observed in psychiatric dis ...

2020

Sensorimotor hallucinations in Parkinson's Disease

Hallucinations in Parkinson’s disease (PD) are one of the most disturbing non-motor symptoms, affect half of the patients, and constitute a major risk factor for adverse clinical outcomes such as psychosis and dementia. Here we report a robotics-based appr ...

2020

Agito ergo sum: Correlates of spatio-temporal motion characteristics during fMRI

Dimitri Nestor Alice Van De Ville, Thomas William Arthur Bolton

The impact of in-scanner motion on functional magnetic resonance imaging (fMRI) data has a notorious reputation in the neuroimaging community. State-of-the-art guidelines advise to scrub out excessively corrupted frames as assessed by a composite framewise ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2020

Interactions between Personality, Depression, Anxiety and Cognition to Understand Early Stage of Alzheimer's Disease

Valérie Rita Madeleine Zufferey

The multifaceted nature of Alzheimer's disease (AD) and Mild cognitive impairment (MCI) can lead to wide inter-individual differences in disease manifestation in terms of brain pathology and cognition. The lack of understanding of phenotypic diversity in A ...

BENTHAM SCIENCE PUBL LTD2020

Evolution of Cortical and White Matter Lesion Load in Early-Stage Multiple Sclerosis: Correlation With Neuroaxonal Damage and Clinical Changes

Meritxell Bach Cuadra, Cristina Granziera, Guillaume Bonnier, Mario Joao Fartaria de Oliveira, Po-Jui Lu

Introduction:Changes in cortical and white matter lesion (CL, WML) load are pivotal metrics to diagnose and monitor multiple sclerosis patients. Yet, the relationship between (i) changes in CL/WML load and disease progression and between (ii) changes in CL ...

FRONTIERS MEDIA SA2020

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