MOOC
Simulation Neurocience
Publications associées (1 000)
A bistable inhibitory optoGPCR for multiplexed optogenetic control of neural circuits
Information is transmitted between brain regions through the release of neurotransmitters from long-range projecting axons. Understanding how the activity of such long-range connections contributes to behavior requires efficient methods for reversibly mani ...
Nature Portfolio2024Fear learning induces synaptic potentiation between engram neurons in the rat lateral amygdala
Henry Markram, Rodrigo de Campos Perin
The lateral amygdala (LA) encodes fear memories by potentiating sensory inputs associated with threats and, in the process, recruits 10-30% of its neurons per fear memory engram. However, how the local network within the LA processes this information and w ...
Nature Portfolio2024Cortical cell assemblies and their underlying connectivity: An in silico study
Michael Reimann, András Ecker, Sirio Bolaños Puchet, James Bryden Isbister, Daniela Egas Santander
Recent developments in experimental techniques have enabled simultaneous recordings from thousands of neurons, enabling the study of functional cell assemblies. However, determining the patterns of synaptic connectivity giving rise to these assemblies rema ...
2024Subcortical correlates of consciousness with human single neuron recordings
Olaf Blanke, Fosco Bernasconi, Nathan Quentin Faivre, Michael Eric Anthony Pereira
Subcortical brain structures such as the basal ganglia or the thalamus are involved in regulating motor and cognitive behavior. However, their contribution to perceptual consciousness is still unclear, due to the inherent difficulties of recording subcorti ...
2024Task-driven neural network models predict neural dynamics of proprioception: Neural network model weights
Alexander Mathis, Alberto Silvio Chiappa, Alessandro Marin Vargas, Axel Bisi
Proprioception tells the brain the state of the body based on distributed sensors in the body. However, the principles that govern proprioceptive processing from those distributed sensors are poorly understood. Here, we employ a task-driven neural network ...
EPFL Infoscience2024Technology and Planning: The Invalides Train Station Project in Paris (1889-1902)
Designed by Just Lisch for the 1900 Exposition Universelle, the Invalides train station gave the French western railway company a more central terminus in Paris, right next to the exhibition pavilions and the river Seine. From 1893 onwards, the project was ...
2024Involvement of prelimbic cortex neurons and related circuits in the acquisition of a cooperative learning by pairs of rats
Maria del Carmen Sandi Perez, Elias Georges Gebara, Ana del Rocio Conde Moro
Social behaviors such as cooperation are crucial for mammals. A deeper knowledge of the neuronal mechanisms underlying cooperation can be beneficial for people suffering from pathologies with impaired social behavior. Our aim was to study the brain activit ...
Springer2024Fast adaptation to rule switching using neuronal surprise
In humans and animals, surprise is a physiological reaction to an unexpected event, but how surprise can be linked to plausible models of neuronal activity is an open problem. We propose a self-supervised spiking neural network model where a surprise signa ...
2024White adipose tissue distribution and amount are associated with increased white matter connectivity
Jean-Philippe Thiran, Gabriel Girard, Elda Fischi Gomez, Philipp Johannes Koch, Liana Okudzhava
Obesity represents a significant public health concern and is linked to various comorbidities and cognitive impairments. Previous research indicates that elevated body mass index (BMI) is associated with structural changes in white matter (WM). However, a ...
Hoboken2024Trio preserves motor synapses and prolongs motor ability during aging
Evelyne Ruchti, Brian Donal McCabe, Soumya Banerjee, Greta Limoni, Samuel William Vernon, Wei Jiao
The decline of motor ability is a hallmark feature of aging and is accompanied by degeneration of motor synaptic terminals. Consistent with this, Drosophila motor synapses undergo characteristic age -dependent structural fragmentation co -incident with dim ...
Cell Press2024