Publications de Hicham Majd | EPFL Graph Search

Capillary-valve-based platform towards cell-on-chip mechanotransduction assays

Martinus Gijs, Dominique Pioletti, Hicham Majd, Christophe Yamahata, Tanja Cloé Hausherr, Arnaud Müller

Reliable in vitro models are required to understand the ability of cells to respond and adapt to mechanical stimuli. To mimic and interface with the microenvironment, lab-on-a-chip devices and microelectromechanical systems (MEMS) provide excellent options ...

Elsevier2013

A novel culture system provides high yields of non-fibrogenic primary dermal fibroblasts for grafting applications

Hicham Majd, Boris Hinz

Amer Soc Cell Biology2011

Coated medical device and method of coating a medical device to reduce, fibrosis and capsule formation

Hicham Majd, Boris Hinz, Giorgio Pietramaggiori

Coating for a medical device comprising cell-adhesive proteins having the ability to reduce fibrous reaction, said coating being in the form of separate islets having an individual area which is less than 12 [mu]m2 and wherein the distance between the isle ...

2010

The covalent attachment of adhesion molecules to silicone membranes for cell stretching applications

Jean-Jacques Meister, Hicham Majd, Lara Buscemi Estefanell, Boris Hinz, Pierre Jean Arnould Wipff

Strain devices with expandable polydimethylsiloxane (PDMS) culture membranes are frequently used to stretch cells in vitro, mimicking mechanically dynamic tissue environments. To immobilize cell-adhesive molecules to the otherwise non-adhesive PDMS substra ...

Elsevier2009

A novel cell culture approach for tissue engineering based on surface expansion

Hicham Majd

Most tissue engineering approaches include the delivery of reparative cells to a damaged host tissue. Generally these cells are sought to be of a stem cell character since they retain a high potential for proliferation and differentiation into diverse phen ...

EPFL2008

A novel method of dynamic culture surface expansion improves mesenchymal stem cell proliferation and phenotype

Hicham Majd, Lara Buscemi Estefanell, Boris Hinz, Pierre Jean Arnould Wipff

Repeated passaging in conventional cell culture reduces pluripotency and proliferation capacity of human mesenchymal stem cells (MSC). We introduce an innovative cell culture method whereby the culture surface is dynamically enlarged during cell proliferat ...

2008

Device for Cell Culture on Deformable Surfaces

Hicham Majd

Device for the in vitro culture of cells comprising: a planar deformable substrate ( 3 ) with a culture surface ( 4 ), substrate deforming means for modifying the size of said culture surface ( 4 ), characterized by the fact that it furthermore comprises: ...

2008