Personne

Heinrich Hofmann

Publications associées (114)

Factors influencing safety and efficacy of intravenous iron-carbohydrate nanomedicines: From production to clinical practice

Iron deficiency is an important subclinical disease affecting over one billion people worldwide. A growing body of clinical records supports the use of intravenous iron-carbohydrate complexes for patients where iron replenishment is necessary and oral iron ...

2020

The impact of synthetic amorphous silica (E 551) on differentiated Caco-2 cells, a model for the human intestinal epithelium

Heinrich Hofmann

For several decades, food-grade synthetic amorphous silica (SAS) have been used as a technological additive to reduce caking of food powders. Human exposure is thus inevitable and safety concerns are taken seriously. The toxicity of silica in general and S ...

PERGAMON-ELSEVIER SCIENCE LTD2020

Functionalization of iron oxide nanoparticles with methacrylate-based monomers for preparation of nanocomposites

Heinrich Hofmann

Nanocomposites with a high and uniform loading of magnetic nanoparticles are very desirable for various applications. In this study, a simple and scalable route for preparing nanocomposites with a high and uniform loading of magnetic nanoparticles is prese ...

AMER INST PHYSICS2018

Beyond Unpredictability: The Importance of Reproducibility in Understanding the Protein Corona of Nanoparticles

Heinrich Hofmann, Diego Chiappe, Lionel André Maurizi, Sandra Caroline Galmarini, Nadia Rachel Von Moos, Noëlie Cayla

While it is well established that the surface of a nanoparticle plays a pivotal role for the protein corona, the vast number of proteins present in biological media render general conclusions about affinities between nanoparticle surfaces and proteins nont ...

AMER CHEMICAL SOC2018

Critical raw materials: A perspective from the materials science community

Heinrich Hofmann

Functional materials are crucial to meet today's societal challenges and needs, such as the transition towards low carbon energy production to reduce climate change, renewable energies and green economy, clean mobility and improved communication. In order ...

ELSEVIER SCIENCE BV2018

Transparent and Robust Silica Coatings with Dual Range Porosity for Enzyme-Based Optical Biosensing

Heinrich Hofmann, Oswaldo Javier Pérez Anguiano, Bernard Wenger, Raphaël Pugin, Emmanuel Scolan

Hierarchically porous transparent silica coatings combine large specific surface area with enhanced pore accessibility for optical biosensing. This paper describes a versatile approach to fabricate optically transparent silica coatings with multiscale poro ...

Wiley-Blackwell2017

Study and characterization of soft magnetic materials for beam intensity monitors at CERN

Heinrich Hofmann, Silvia Aguilera Murciano

At CERN, the circulating beam current measurement is provided by two types of transformers, the DC Current Transformer (DCCT) and the Fast Beam Current Transformer (FBCT). Each transformer is built based on toroidal cores made from a magnetic material. Dep ...

Iop Publishing Ltd2017

Hydrothermal growth of iron oxide NPs with a uniform size distribution for magnetically induced hyperthermia: Structural, colloidal and magnetic properties

Heinrich Hofmann, Kurt Schenk, Olivier Jordan

Magnetic iron oxide nanoparticles with a narrow size distribution were synthesized by hydrothermally treating suspensions of iron oxide nanoparticles. Ricinoleic-acid-coated magnetic nanoparticles were co precipitated at room temperature from an aqueous so ...

Elsevier2017

Assessment of nanoparticles’ safety: corrected absorbance-based toxicity test

Heinrich Hofmann, Marijana Mionic Ebersold, Débora Bonvin

We developed a method to correct absorbance-based toxicity tests to remove the influence of the deposited dose of nano-particles. As a model of absorbance-based toxicity tests, we chose the frequently used MTS test. The corrected cell viabilities obtained ...

Royal Soc Chemistry2017

Methods of protein corona isolation for magnetic nanoparticles

Heinrich Hofmann, Diego Chiappe, Marc Moniatte, Marijana Mionic Ebersold, Débora Bonvin

Nanoparticles (NPs) in contact with a biological environment get covered by proteins and some are loosely bound and some are tightly bound. The latter form a hard protein corona (HPC) which is known to determine their biological behavior. Therefore, in ord ...

Royal Soc Chemistry2017

Graph Chatbot

Chattez avec Graph Search

Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.

AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.

Connectez-vous pour utiliser Chat avec Graph Search