Hubert van den Bergh

À propos
Confidentialité
Mentions légales

Graph Chatbot

Publications associées (145)

A streamlined search technology for identification of synergistic drug combinations

Hubert van den Bergh, Paul Joseph Dyson, Patrycja Nowak-Sliwinska

A major key to improvement of cancer therapy is the combination of drugs. Mixing drugs that already exist on the market may offer an attractive alternative. Here we report on a new model-based streamlined feedback system control (s-FSC) method, based on a ...

Nature Publishing Group2015

Rapid optimization of drug combinations for the optimal angiostatic treatment of cancer

Paul Joseph Dyson, Hubert van den Bergh, Patrycja Nowak-Sliwinska

Drug combinations can improve angiostatic cancer treatment efficacy and enable the reduction of side effects and drug resistance. Combining drugs is non-trivial due to the high number of possibilities. We applied a feedback system control (FSC) technique w ...

2015

Discovery of a low order drug-cell response surface for applications in personalized medicine

Hubert van den Bergh, Patrycja Nowak-Sliwinska, Yiyang Li

The cell is a complex system involving numerous components, which may often interact in a non-linear dynamic manner. Diseases at the cellular level are thus likely to involve multiple cellular constituents and pathways. As some drugs, or drug combinations, ...

Iop Publishing Ltd2014

Sequential combination of axitinib with photodynamic therapy synergistically delays tumor growth in a preclinical model of human ovarian carcinoma

Hubert van den Bergh, Patrycja Nowak-Sliwinska, Débora Bonvin

Springer2014

Ruthenium clusters as new class of anti-angiogenic agent

Paul Joseph Dyson, Hubert van den Bergh, Patrycja Nowak-Sliwinska, Alexey Nazarov

Springer2014

Combination of low-dose angiostatic tyrosine kinase inhibitors improve photodynamic therapy in human carcinoma models: lack of vascular normalization

Paul Joseph Dyson, Hubert van den Bergh, Patrycja Nowak-Sliwinska, Débora Bonvin

Springer2014

A feedback loop optimized vascular targeted drug combination for the treatment of cancer

Paul Joseph Dyson, Hubert van den Bergh, Patrycja Nowak-Sliwinska

Springer2014

Optical spectroscopy of the bladder washout fluid to optimize fluorescence cystoscopy with Hexvix

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Blaise Lovisa, Carla Martoccia

Fluorescence cystoscopy enhances detection of early bladder cancer. Water used to inflate the bladder during the procedure rapidly contains urine, which may contain fluorochromes. This frequently degrades fluorescence images. Samples of bladder washout flu ...

SPIE Society of Photo-optical Instrumentation Engineers2014

In vivo measurement of tissue oxygenation by time-resolved luminescence spectroscopy: advantageous properties of dichlorotris(1, 10-phenanthroline)-ruthenium(II) hydrate

Hubert van den Bergh, Georges Wagnières, Patrycja Nowak-Sliwinska, Matthieu Philippe Emmanuel Zellweger, Veronika Huntosova, Sandrine Gay, Senthil Kumar Rajendran

Measuring tissue oxygenation in vivo is of interest in fundamental biological as well as medical applications. One minimally invasive approach to assess the oxygen partial pressure in tissue (pO(2)) is to measure the oxygen-dependent luminescence lifetime ...

SPIE Society of Photo-optical Instrumentation Engineers2014

Correlation between Protoporphyrin IX Fluorescence Intensity, Photobleaching, Pain and Clinical Outcome of Actinic Keratosis Treated by Photodynamic Therapy

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Jérôme Barge, Filippo Piffaretti

Background: Photodynamic therapy (PDT) with Metvix® is a good therapeutic option to treat actinic keratosis, but it presents drawbacks (pain, lesion recurrences, heterogeneous outcome), emphasizing the possible need to individualize treatment. Objective: W ...

Karger2013

Page 2 sur 15