Pierre Marquet

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Publications associées (65)

Automated multi-parameter measurement of cardiomyocytes dynamics with digital holographic microscopy

Gerardo Turcatti, Benjamin Rappaz, Pierre Marquet

Compounds tested during drug development may have adverse effects on the heart; therefore all new chemical entities have to undergo extensive preclinical assessment for cardiac liability. Conventional intensity-based imaging techniques are not robust enoug ...

Optical Society of America2015

Astrocyte swelling in response to neural activation: role of cotransporters

Pierre Magistretti, Pierre Marquet, Pascal Jourdain, Daniel Boss, Kaspar Rothenfusser

Wiley-Blackwell2015

The human CFTR protein expressed in CHO cells activates aquaporin-3 in a cAMP-dependent pathway: study by digital holographic microscopy

Pierre Magistretti, Pierre Marquet, Pascal Jourdain, Sylvain Eric Lengacher

The transmembrane water movements during cellular processes and their relationship to ionic channel activity remain largely unknown. As an example, in epithelial cells it was proposed that the movement of water could be directly linked to cystic fibrosis t ...

Company of Biologists2014

High throughput second harmonic imaging for label-free biological applications

Pierre Magistretti, Sylvie Roke, Aleksandra Radenovic, Carlos Alberto Macias Romero, Pascal Jourdain, Orly Bagunu Tarun, Pierre Marquet, Vitalijs Zubkovs, Marie Eve Pascale Didier

Second harmonic generation (SHG) is inherently sensitive to the absence of spatial centrosymmetry, which can render it intrinsically sensitive to interfacial processes, chemical changes and electrochemical responses. Here, we seek to improve the imaging th ...

Optical Society of America2014

Increased activation in Broca's area after cognitive remediation in schizophrenia

Pierre Magistretti, Pierre Marquet

Functional magnetic resonance imaging (fMRI) was used to measure changes in cerebral activity in patients with schizophrenia after participation in the Cognitive Remediation Program for Schizophrenia and other related disorders (RECOS). As RECOS therapists ...

Elsevier2014

Loss of Protein Tyr-phosphorylation During in vitro Storage of Human Erythrocytes: Impact on RBC Morphology

Gerardo Turcatti, Niels Erik Lion, Benjamin Rappaz, Pierre Marquet, Michel Prudent

Wiley-Blackwell2014

Measurement of absolute cell volume, osmotic membrane water permeability, and refractive index of transmembrane water and solute flux by digital holographic microscopy

Pierre Magistretti, Christian Depeursinge, Pierre Marquet, Pascal Jourdain, Daniel Boss

A dual-wavelength digital holographic microscope to measure absolute volume of living cells is proposed. The optical setup allows us to reconstruct two quantitative phase contrast images at two different wavelengths from a single hologram acquisition. When ...

SPIE Society of Photo-optical Instrumentation Engineers2013

Automated quantitative analysis of 3D morphology and mean corpuscular hemoglobin in human red blood cells stored in different periods

Pierre Marquet, Daniel Boss

Quantitative phase (QP) images of red blood cells (RBCs), which are obtained by off-axis digital holographic microscopy, can provide quantitative information about three-dimensional (3D) morphology of human RBCs and the characteristic properties such as me ...

Optical Soc Amer2013

Marker-free phase nanoscopy

Pierre Magistretti, Christian Depeursinge, Pierre Marquet, Nicolas Pavillon, Pascal Jourdain, Daniel Boss, Yann Jérôme Michel Pascal Cotte, Muhammed Fatih Toy

We introduce a microscopic method that determines quantitative optical properties beyond the optical diffraction limit and allows direct imaging of unstained living biological specimens. In established holographic microscopy, complex fields are measured us ...

Nature Publishing Group2013

Automated segmentation of multiple red blood cells with digital holographic microscopy

Pierre Marquet, Daniel Boss

We present a method to automatically segment red blood cells (RBCs) visualized by digital holographic microscopy (DHM), which is based on the marker-controlled watershed algorithm. Quantitative phase images of RBCs can be obtained by using off-axis DHM alo ...

SPIE Society of Photo-optical Instrumentation Engineers2013

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