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The use of dyes has been helpful for the photodiagnosis of small cancers accessible to endoscopic examn. An important limiting factor of this technol. is that the presently used fluorescent dye mixt. has a relatively poor capacity to accumulate preferentia ...
1992
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The timing has been optimized of photodetection (and possibly also phototherapy) of early cancer in the upper aerodigestive tract and bronchi and the relative concn. of fluorescent components of Photofrin II measured in patients as a function of the time a ...
1991
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New results are presented on the pharmacokinetics of the fluorescing fraction of Photofrin II in patients with an early cancer in the oesophagus or the buccal cavity. The light-induced fluorescence signal shows a relatively high contrast between tumor and ...
1992
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The efficacy of photodynamic therapy (PDT) alone was evaluated on 41 ‘early’ squamous cell carcinomas of the pharynx (10), oesophagus (15) and tracheo-bronchial tree (16). All lesions but two were synchronous second primaries in ENT-patients suffering from ...
An apparatus is designed and realized to detect "early" cancer at the surface of the hollow organs in the human body by endoscopic means. The tumor is localized by the laser induced fluorescence of a dye (HPD) which concentrates selectively in the neoplast ...
A fluorescence imaging device applied to the detection of early cancer is described. The app. is based on the imaging of laser-induced fluorescence of a dye that localizes in a tumor with a higher concn. than in the surrounding normal tissue after i.v. inj ...