Publications de Fahd Azzabi Zouraq

Low temperature and mTOR inhibition favor stem cell maintenance in human keratinocyte cultures

Kai Johnsson, Yann Barrandon, Johannes Alexander Mosig, Thomas Michael Braschler, Ariane Rochat, Jean-Baptiste Bureau, Fahd Azzabi Zouraq, Mako Kamiya

Adult autologous human epidermal stem cells can be extensively expanded ex vivo for cell and gene therapy. Identifying the mechanisms involved in stem cell maintenance and defining culture conditions to maintain stemness is critical, because an inadequate ...

WILEY2023

Low temperature and mTOR inhibition favor human epidermal stem cell maintenance

Juan Ramon Mosig, Kai Johnsson, Yann Barrandon, Johannes Alexander Mosig, Thomas Michael Braschler, Ariane Rochat, Jean-Baptiste Bureau, Fahd Azzabi Zouraq

ELSEVIER SCIENCE INC2023

Target of rapamycin modulators of and use thereof

Yann Barrandon, Fahd Azzabi Zouraq

The present invention is related to new molecules capable of interacting with target of rapamycin (TOR) transcriptional complex. In particular, the present invention provides novel nucleic acid molecules, processes for production thereof, kits containing t ...

2009

Mammalian TOR modulates transcription through TORRID sequences

Yann Barrandon, Fahd Azzabi Zouraq

Nature Publishing Group2008

Mammalian TOR as a central modulator of the transcriptional response of keratinocyte stem cells to small temperature variations

Fahd Azzabi Zouraq

Being in the layer at the interface of the body with the outside world, keratinocyte stem cells constantly adapt and respond to environmental cues such as temperature and oxygen. However, until now, experiments involving temperature have only examined cold ...

EPFL2008