Publications de Joël Stéphane Rossier

About the Electrospray Ionization Source in Mass Spectrometry: Electrochemistry and On-chip Reactions

Hubert Girault, Niels Erik Lion, Christophe Roussel, Manuel Alejandro Méndez Agudelo, Michel Prudent, Joël Stéphane Rossier, Bin Su

The present work shows that the electrochemical properties of electrospray ionization (ESI) can be used to add functions to the process. As example, we show how the choice of the electrode material can be used to study interactions between metal ions and b ...

2009

Magnetic forces produced by rectangular permanent magnets in static microsystems

Hubert Girault, Joël Stéphane Rossier, Anne-Laure Gassner, Mélanie Abonnenc, Hong-Xu Chen

Finite element numerical simulations were carried out in 2D geometries to map the magnetic field and force distribution produced by rectangular permanent magnets as a function of their size and position with respect to a microchannel. A single magnet, two ...

2009

Microfabricated Dual Sprayer for On-Line Mass Tagging of Phosphopeptides

Hubert Girault, Niels Erik Lion, Michel Prudent, Joël Stéphane Rossier

Phosphopeptides tagging reactions by dinuclear zinc(II) complexes (1,3-bis[bis(2-pyridylmethyl)amino]-propan- 2-olato dizinc(II)3+, called tag) were performed with a dual-channel microsprayer in electrospray ionization mass spectrometry. The reaction is fi ...

2008

Mechanical control of fluids in micro-analytical devices

Hubert Girault, Joël Stéphane Rossier, Joël Rossier, Xiaoxia Bai

An apparatus for manipulating fluid samples comprises a micro-chip device having first and second covered channels, each channel having openings at both ends. The channels intersect to form a common intersection. Three of the openings of the channels are c ...

2006

Thin chip microsprayer system coupled to quadrupole time-of-flight mass spectrometer for glycoconjugate analysis

Hubert Girault, Niels Erik Lion, Joël Stéphane Rossier

A thin chip polymer-based microsprayer has been coupled to a hybrid quadrupole time-of-flight mass spectrometer (QTOF MS) and introduced in carbohydrate research. The feasibility of the approach is demonstrated for mapping, sequencing and structural elucid ...

Royal Society of Chemistry2005

Editorial: Microfluidics in system biology

Hubert Girault, Niels Erik Lion, Joël Stéphane Rossier

2005

Thin-Chip Microspray System for High-Performance Fourier-Transform Ion-Cyclotron Resonance Mass Spectrometry of Biopolymers

Hubert Girault, Niels Erik Lion, Joël Stéphane Rossier

Wiley-VCH Verlag GmbH2003

On-line electrochemical tagging of cysteines in proteins during nanospray

Hubert Girault, Joël Stéphane Rossier, Tatiana Rohner

Elsevier2002

Protein purification by Off-Gel electrophoresis

Hubert Girault, Joël Stéphane Rossier

2002

Polymer microchips bonded by O2-plasma activation

Hubert Girault, Joël Stéphane Rossier, Nicolas Xanthopoulos

This paper presents a fabrication of polymer microchips with homogeneous material technique due to surface treatment by plasma before sealing. UV laser photoablation was used for fast prototyping of microstructures, and oxygen plasma was used as a surface ...

2002