Publications de Nicola Tirelli

Characterization of the Network Structure of PEG Diacrylate Hydrogels Formed in the Presence of N-Vinyl Pyrrolidone

PEGDA hydrogels copolymerized with NVP using free-radical photopolymerization are used in biomedical applications. These networks consist of a poly(acrylate-co-vinyl pyrrolidone) backbone crosslinked with PEG chains whose crosslink density is dependent on ...

Wiley-V C H Verlag Gmbh2014

Methode pour la preparation des copolymeres blocs pour systemes auto-assembles multifonctionnels

Jeffrey Alan Hubbell, Nicola Tirelli

The invention provides methods for the preparation of multiblock copolymers, dispersions of multiblock copolymers, vesicles and micelles containing multiblock copolymers, and oxidative degradation products of multiblock copolymers. ...

2012

Functionalization of polysulfide nanoparticles and their performance as circulating carriers

Jeffrey Alan Hubbell, Nicola Tirelli, Annemie Rehor

We here present an evaluation of the carrier performance of nanoparticles that are biofunctional, i.e. derivatized to provide a controlled biological activity, and environmentally responsive, since they respond to the presence of oxidants. In particular, w ...

2008

Coating hydrophobic surfaces with amphiphilic thioethers to reduce protein adsorption and cell adhesion

Jeffrey Alan Hubbell, Nicola Tirelli

The present invention provides methods and apparatus for coating surfaces with specially designed thioethers and amphiphilic thioethers that reduce protein adsorption and/or cell adhesion. This reduction may be achieved, for example, by controlling the spa ...

2008

Glucose sensitivity through oxidation responsiveness. An example of cascade-responsive nano-sensors

Jeffrey Alan Hubbell, Nicola Tirelli, Annemie Rehor

Oxidn.-sensitive nanoparticles have been decorated with an oxidizing enzyme (glucose oxidase) for release behavior that is responsive to the presence of the enzyme substrate (glucose). [on SciFinder (R)] ...

Royal Society of Chemistry2005