Publications de Raphaël Tornay

Rapid, Sensitive and Real-Time Multiplexing Platform for the Analysis of Protein and Nucleic-Acid Biomarkers

Philippe Renaud, Nicolas Demierre, Raphaël Tornay, Lucienne Lagopoulos, David Bernasconi

We describe a multiplexing technology, named Evalution, based on novel digitally encoded microparticles in microfluidic channels. Quantitative multiplexing is becoming increasingly important for research and routine clinical diagnostics, but fast, easy-to- ...

Amer Chemical Soc2015

Separation of platelets from other blood cells in continuous-flow by dielectrophoresis field-flow-fractionation

Philippe Renaud, Niccolo Piacentini, Raphaël Tornay

We present a microfluidic device capable of separating platelets from other blood cells in continuous flow using dielectrophoresis field-flow-fractionation. The use of hydrodynamic focusing in combination with the application of a dielectrophoretic force a ...

American Institute of Physics2011

Cell viability assessment by flow cytometry using yeast as cell model

Philippe Renaud, Nina Buffi, Niccolo Piacentini, Raphaël Tornay

This paper reports the new combination of cell sorting and counting capabilities on a single device. Most state-of-the-art devices combining these technologies use optical techniques requiring complicated experimental setups and labeled samples. The use of ...

2011

Dielectrophoresis-based continuous-flow particle microreactor

Raphaël Tornay

This thesis mainly deals with the integration of a microfluidic system for the extraction of micrometric and submicrometric particles from a solution. Traditional methods take from several minutes to hours to separate particles from a solution. Microfluidi ...

EPFL2009

Wide channel dielectrophoresis-based particle exchanger with electrophoretic diffusion compensation

Philippe Renaud, Thomas Michael Braschler, Raphaël Tornay

We present here a microfluidic device for the chemical modification of particles. In order to alleviate diffusive mixing issues beads are pushed from a starting buffer to a reagent over a wide channel by an array of shifted electrodes. We also show that th ...

2009

Dielectrophoresis-based particle exchanger for the manipulation and surface functionalization of particles

Philippe Renaud, Heinrich Hofmann, Jeffrey Alan Hubbell, Thomas Michael Braschler, Nicolas Demierre, Benedikt Steitz, Raphaël Tornay, Andrija Finka

We present a microfluidic device where micro- and nanoparticles can be continuously functionalized in flow. This device relies on an element called particle exchanger, which allows for particles to be taken from one medium and exposed to some reagent while ...

2008

A virtual valve for smooth contamination-free flow switching

Philippe Renaud, Thomas Michael Braschler, Harald Van Lintel, Nicolas Demierre, Anja Kunze, Mario Schlund, Raphaël Tornay, Joël Theytaz, Grazia Loche

We present a channel geometry that allows for clean switching between different inlets of a microchip without any contamination of the inlets or the downstream flow. We drive this virtual valve with a pneumatic pressure setup that minimizes disturbance of ...

2007

Electrical detection and ejection of beads in a one-cell-per-drop microdispenser

Philippe Renaud, Raphaël Tornay

2007