Caroline Vandevyver

Cette personne n’est plus à l’EPFL

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Publications associées (44)

Time-Resolved Luminescence for Immunohistochemical Detection of Cancer Biomarkers in a Lab-on-a-Chip

Martinus Gijs, Jean-Claude Bünzli, Caroline Vandevyver, Ata Tuna Ciftlik, Venkataragavalu Sivagnanam

2009

On-chip immunoassay using electrostatic assembly of streptavidin-coated bead micropatterns

Martinus Gijs, Caroline Vandevyver, Venkataragavalu Sivagnanam

We propose an original concept for a sandwich immunoassay that is completely performed on-chip using streptavidin-coated beads as substrate. The latter are electrostatically self-assembled on aminosilane micropatterns at the bottom of a microfluidic channe ...

2009

On-chip immunoassay using electrostatic assembly of streptavidin-coated bead micropatterns

Martinus Gijs, Caroline Vandevyver, Venkataragavalu Sivagnanam, Hui Yang, Bo Song

2009

Luminescent Bimetallic Lanthanide Bioprobes for Cellular Imaging with Excitation in the Visible-Light Range

Jean-Claude Bünzli, Anne-Sophie Chauvin, Frédéric Gumy, Caroline Vandevyver, Bo Song

A series of homoditopic ligands H2LCX (X=4–6) has been designed to self-assemble with lanthanide ions (LnIII), resulting in neutral bimetallic helicates of overall composition [Ln2ACHTUNGTRENUNG(LCX)3] with the aim of testing the influence of substituents ...

2009

Magnetic beads retention device for sandwich immunoassay: comparison of off-chip and on-chip antibody incubation

Martinus Gijs, Caroline Vandevyver, Frédéric Lacharme

We use magnetic microbeads, which are magnetically self-assembled in chains in a microfluidic chip, as reaction substrates to implement two different sandwich immunoassay protocols for the detection of mouse monoclonal target antibodies. The magnetic chain ...

Springer-Verlag2009

Screening of a Human Antibody Phage Display Library Against a Peptide Antigen Using Stimuli-Responsive Bioconjugates

Caroline Vandevyver, Dorothée Dumoulin

A synthetic antibody phage library, (ETH-2) was screened against the MUC-1 peptide. Two standard methods were used, namely screening on immunotubes coated with the peptide antigen and on streptavidin-coated paramagnetic particles together with a biotinylat ...

2008

Full on-chip nanoliter immuno-assay by geometrical magnetic trapping of nanoparticle chains

Martinus Gijs, Caroline Vandevyver, Frédéric Lacharme

We propose an original concept to perform a complete on-chip sandwich immunoassay on magnetic nanoparticles that are self-assembled in chains in a uniform magnetic field. The magnetic chains are retained over periodically enlarged cross sections of a micro ...

2008

Micropatterning of protein-functionalized magnetic beads on glass using electrostatic self-assembly

Martinus Gijs, Abdeljalil Sayah, Caroline Vandevyver, Venkataragavalu Sivagnanam

We demonstrate a simple and fast method for self-assembly-driven micropatterning of protein functionalized magnetic beads on glass. We use positively charged aminosilane micro-patterns as template for selective immobilization of streptavidin-coated beads b ...

2008