Publications de Jan Overney | EPFL Graph Search

Modelling Small-Scale Drifting Snow with a Lagrangian Stochastic Model Based on Large-Eddy Simulations

Michael Lehning, Marc Parlange, Marc Diebold, Jan Overney, Gian-Duri Lieberherr

Observations of drifting snow on small scales have shown that, in spite of nearly steady winds, the snow mass flux can strongly fluctuate in time and space. Most drifting snow models, however, are not able to describe drifting snow accurately over short ti ...

Springer Verlag2014

A computational framework for the design of optimal protein synthesis

Vassily Hatzimanikatis, Julien Racle, Jan Overney

Despite the establishment of design principles to optimize codon choice for heterologous expression vector design, the relationship between codon sequence and final protein yield remains poorly understood. In this work, we present a computational framework ...

Wiley-Blackwell2012

A multichamber fluidic device for 3D cultures under interstitial flow with live imaging: Development, characterization, and applications

Melody Swartz, Jan Overney, James Brandon Dixon, Adrian Chung-Kai Shieh, Carmen Bonvin

Interstitial flow is an important biophysical cue that can affect capillary morphogenesis, tumor cell migration, and fibroblast remodeling of the extracellular matrix, among others. Current models that incorporate interstitial flow and that are suitable fo ...

Wiley-Blackwell2010

The Effects of Building Representation and Clustering in Large-Eddy Simulations of Flows in Urban Canopies

Marc Parlange, Jan Overney

We perform large-eddy simulations of neutral atmospheric boundary-layer flow over a cluster of buildings surrounded by relatively flat terrain. The first investigated question is the effect of the level of building detail that can be included in the numeri ...

2009

Mimicking interstitial microenvironments for lymphatic capillary tissue

Melody Swartz, Jan Overney

2008