Publications de Sandor Kasas | EPFL Graph Search

Nanomotion-Based Drug Sensitivity Prediction in Ovarian and Colon Cancer Cell Lines Using Machine Learning

Cancer drug resistance remains a critical challenge in oncology, demanding rapid and reliable diagnostic tools to assess tumor cell susceptibility to treatment. This study presents a nanomotion-based drug susceptibility testing (DST) approach, integrating ...

American Chemical Society (ACS)2025

Effect of surfactants on inactivation of Bacillus subtilis spores by chlorine

Urs von Gunten, Sandor Kasas, María Inés Villalba, Tianqi Zhang

Bacterial spores pose significant risks to human health, yet the inactivation of spores is challenging due to their unique structures and chemical compositions. This study investigated the synergistic effect between surfactants and chlorine on the inactiva ...

2025

Rapid assessment of bisphenol A toxicity on fish eggs using optical nanomotion detection

Sandor Kasas

Fish have a vital role in environment and human nutrition worldwide. Assessing the health of fish reproductive cells is crucial for both wild populations and aquaculture, serving as a key indicator of ecosystem health and the safety of seafood. Bisphenol A ...

Oxford University Press (OUP)2025

Accurate and rapid antibiotic susceptibility testing using a machine learning-assisted nanomotion technology platform

Sandor Kasas, Anthony Vocat, Gino Cathomen, Eric Delarze, Florian Tagini, Laura Munch

Antimicrobial resistance (AMR) is a major public health threat, reducing treatment options for infected patients. AMR is promoted by a lack of access to rapid antibiotic susceptibility tests (ASTs). Accelerated ASTs can identify effective antibiotics for t ...

Nature Portfolio2024

A simplified version of rapid susceptibility testing of bacteria and yeasts using optical nanomotion detection

Sandor Kasas, María Inés Villalba, Sahand Jamal Rahi, Vojislav Gligorovski

We present a novel optical nanomotion-based rapid antibiotic and antifungal susceptibility test. The technique consisted of studying the effects of antibiotics or antifungals on the nanometric scale displacements of bacteria or yeasts to assess their sensi ...

Frontiers Media SA2024

An Optical Fiber-Based Nanomotion Sensor for Rapid Antibiotic and Antifungal Susceptibility Tests

Giovanni Dietler, Sandor Kasas, María Inés Villalba, Serguei Sekatski, Anne-Céline Verenna Kohler, Jiangtao Zhou, Leonardo Venturelli

The emergence of antibiotic and antifungal resistant microorganisms represents nowadays a major public health issue that might push humanity into a post-antibiotic/antifungal era. One of the approaches to avoid such a catastrophe is to advance rapid antibi ...

Amer Chemical Soc2024

Cellular nanomotion as a new signature of life

Sandor Kasas

Frontiers Media SA2024

Machine learning method for the classification of the state of living organisms' oscillations

Sandor Kasas, María Inés Villalba

The World Health Organization highlights the urgent need to address the global threat posed by antibiotic-resistant bacteria. Efficient and rapid detection of bacterial response to antibiotics and their virulence state is crucial for the effective treatmen ...

Frontiers Media Sa2024

Optical Nanomotion Detection to Rapidly Discriminate between Fungicidal and Fungistatic Effects of Antifungals on Single-Cell Candida albicans

Sandor Kasas, María Inés Villalba

Candida albicans is an emerging pathogen that poses a significant challenge due to its multidrug-resistant nature. There are two types of antifungal agents, fungicidal and fungistatic, with distinct mechanisms of action against fungal pathogens. Fungicidal ...

MDPI AG2024

Editorial: New marketable discoveries in nanobiotechnology

Sandor Kasas

Lausanne2024