Publications de Cristian Carmeli

DBnorm as an R package for the comparison and selection of appropriate statistical methods for batch effect correction in metabolomic studies

Nicolas Jean Philippe Guex, Murielle Bochud, Cristian Carmeli, Aurélien Thomas, Tiziana Caputo

As a powerful phenotyping technology, metabolomics provides new opportunities in biomarker discovery through metabolome-wide association studies (MWAS) and the identification of metabolites having a regulatory effect in various biological processes. While ...

Nature Research2021

Differential regulation of RNA polymerase III genes during liver regeneration

Olivier Martin, Bart Deplancke, Felix Naef, Jacques Rougemont, Marion Leleu, Nicolas Jean Philippe Guex, Fabrice David, Kyle Gustafson, Dominic Villeneuve, Cristian Carmeli

Mouse liver regeneration after partial hepatectomy involves cells in the remaining tissue synchronously entering the cell division cycle. We have used this system and H3K4me3, Pol II and Pol III profiling to characterize adaptations in Pol III transcriptio ...

Oxford University Press (OUP)2019

Evolution of source EEG synchronization in early Alzheimer's disease

Reto Meuli, Alireza Khadivi, Cristian Carmeli

Alzheimer's disease (AD) disrupts functional connectivity in distributed cortical networks. We analyzed changes in the S-estimator, a measure of multivariate intraregional synchronization, in electroencephalogram (EEG) source space in 15 mild AD patients v ...

Elsevier2013

Estimating interdependences in networks of weakly coupled deterministic systems

Oscar De Feo, Cristian Carmeli

The extraction of information from measured data about the interactions taking place in a network of systems is a key topic in modern applied sciences. This topic has been traditionally addressed considering bivariate time series, providing methods that ar ...

2008

A Novel Interhemispheric Interaction: Modulation of Neuronal Cooperativity in the Visual Areas

Oscar De Feo, Cristian Carmeli, Giorgio Innocenti

2007

Assessing Dependences within Multivariate Time Series Partializing the Knowledge of Thirds

Oscar De Feo, Cristian Carmeli

A method to estimate from multivariate measurements the dependences within a network of coupled dynamical systems is proposed. The method is non-parametric and resorts to a statistics of the eigen-spectrums of the time series partial correlation matrices. ...

2006

State Change Detection using Multivariate Synchronization Measure from Physiological Signals

Martin Hasler, Cristian Carmeli, Kumiko Oshima

The cardiovascular system can be macro-modelled as a collection of coupled oscillators. Recently, the use of mutual couplings of these oscillators to characterize the state of the system during anaesthesia has been proposed. Assuming that the synchronizati ...

2006

Assessing cooperative behavior in dynamical networks with applications to brain data

Cristian Carmeli

Capturing the collective coherent spatiotemporal activity from measured data in large ensembles of coupled nonlinear sub-systems has revealed to be a key topic in many areas of applied sciences. Currently, this topic is addressed by considering multivariat ...

EPFL2006

State Change Detection Using Multivariate Synchronization Measure from Physiological Signals

Martin Hasler, Cristian Carmeli, Kumiko Oshima

The cardiovascular system can be macro-modelled as a collection of coupled oscillators. Recently, the use of mutual couplings of these oscillators to characterize the state of the system during anaesthesia has been proposed. Assuming that the synchronizati ...

2006

Inferring global dynamics and connectivity of neural ensembles through EEG signals

Oscar De Feo, Cristian Carmeli, Giorgio Innocenti

2005