Publications de Adriano Garonna

The Mechanical Environment Modulates Intracellular Calcium Oscillation Activities of Myofibroblasts

Boris Hinz, Adriano Garonna, Lysianne Follonier Castella

Myofibroblast contraction is fundamental in the excessive tissue remodeling that is characteristic of fibrotic tissue contractures. Tissue remodeling during development of fibrosis leads to gradually increasing stiffness of the extracellular matrix. We pro ...

Public Library Science2013

Cyclotron Designs for Ion Beam Therapy with Cyclinacs

Adriano Garonna

This thesis presents new superconducting compact (as opposed to separated-sector ) cyclotron designs for injection in CABOTO, a linac developed by the TERA Foundation delivering C6+/H2+ beams up to 400 MeV/u for ion beam therapy. This association of a vari ...

EPFL2011

Accelerators for hadrontherapy: From Lawrence cyclotrons to linacs

Adriano Garonna, Alberto Degiovanni

Hadrontherapy with protons and carbon ions is a fast developing methodology in radiation oncology. The accelerators used and planned for this purpose are reviewed starting from the cyclotrons used in the thirties. As discussed in the first part of this pap ...

2010

Cyclinac medical accelerators using pulsed C6+/H + 2 ion sources

Adriano Garonna, Alberto Degiovanni

Charged particle therapy, or so-called hadrontherapy, is developing very rapidly. There is large pressure on the scientific community to deliver dedicated accelerators, providing the best possible treatment modalities at the lowest cost. In this context, t ...

2010