Publications de Karen Cheung | EPFL Graph Search

Demonstration of cortical recording using novel flexible polymer neural probes

Philippe Renaud, Arnaud Bertsch, André Mercanzini, Philippe Colin, Marc Jasper Boers, Jean-Charles Bensadoun, Karen Cheung

We present the fabrication, characterization, use in cortical recording and histological results of a flexible implantable neural probe. The microfabricated device is implemented in polyimide and platinum providing mechanical flexibility, high quality elec ...

2008

Demonstration of cortical recording and reduced inflammatory response using flexible polymer neural probes

Philippe Renaud, Arnaud Bertsch, André Mercanzini, Philippe Colin, Marc Jasper Boers, Jean-Charles Bensadoun, Karen Cheung

2007

Flexible polyimide microelectrode array for in vivo recordings and current source density analysis

Philippe Renaud, Karen Cheung

This work presents implantable, flexible polymer-based probes with embedded microelectrodes for acute and chronic neural recordings in vivo, as tested on rodents. Acute recordings using this array were done in mice under urethane anesthesia and compared to ...

Elsevier2007

BioMEMS for medicine: On-chip cell characterization and implantable microelectrodes

Philippe Renaud, Karen Cheung

This paper surveys a few of the emerging bioMEMS technologies at EPFL for improved, inexpensive health care. The lab-on-a-chip systems use dielectrophoretic forces to direct cell movement within microfluidic networks and impedance spectroscopy for label-fr ...

2006

Impedance spectroscopy flow cytometry: On-chip label-free cell differentiation

Philippe Renaud, Shady Didier Gawad, Karen Cheung

Background: The microfabricated impedance spectroscopy flow cytometer used in this study permits rapid dielectric characterization of a cell population with a simple microfluidic channel. Impedance measurements over a wide frequency range provide informati ...

2005

Dielectric spectroscopy in a micromachined flow cytometer: theoretical and practical considerations

Philippe Renaud, Arnaud Bertsch, Shady Didier Gawad, Urban Seger, Karen Cheung

We propose a model to determine the influence of different cell properties, such as size, membrane capacitance and cytoplasm conductivity, on the impedance spectrum as measured in a microfabricated cytometer. A dielectric sphere of equivalent complex permi ...

2004