Publications de David Jegger | EPFL Graph Search

Effects of an aging vascular model on healthy and diseased hearts

Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, David Jegger, Patrick Segers

The vitamin D(3) and nicotine (VDN) model is a model of isolated systolic hypertension (ISH) due to arterial calcification raising arterial stiffness and vascular impedance similar to an aged and stiffened arterial tree. We therefore analyzed the impact of ...

2007

The effect of a myocardial infarction on the normalized time-varying elastance curve

Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, David Jegger

It has been suggested that the shape of the normalized time-varying elastance curve [E(n)(t(n))] is conserved in different cardiac pathologies. We hypothesize, however, that the E(n)(t(n)) differs quantitatively after myocardial infarction (MI). Sprague-Da ...

2006

Effects of a stiffened arterial tree on ventricular-arterial coupling in healthy and diseased hearts

David Jegger

In this thesis we study ventricular-arterial coupling in rodents under the influence of arterial stiffening and myocardial infarction (MI), combination of the two considered as a novel cardiovascular research model for diseased hearts pumping against an ag ...

EPFL2006

Noninvasive Doppler-derived myocardial performance index in rats with myocardial infarction: validation and correlation by conductance catheter

Nikolaos Stergiopoulos, David Jegger, Patrick Segers

The rodent model of myocardial infarction (MI) is extensively used in heart failure studies. However, long-term follow-up of echocardiographic left ventricular (LV) function parameters such as the myocardial performance index (MPI) and its ratio with the f ...

2005