Personne

Stefano Tugulu

Cette personne n’est plus à l’EPFL

Publications associées (10)

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Sediment traps with guiding channel and hybrid check dams improve controlled sediment retention

Mário Jorge Rodrigues Pereira Da Franca, Sebastian Schwindt, Stefano Tugulu, Alessandro Reffo

Sediment traps with partially open check dams are crucial elements for flood protection in alpine regions. The trapping of sediment is necessary when intense sediment transport occurs during floods that may endanger urban areas at downstream river reaches. ...

2018

Surface Modification of Polydimethylsiloxane Substrates with Nonfouling Poly(Poly(ethylene glycol)methacrylate) Brushes

Harm-Anton Klok, Stefano Tugulu

This contribution presents a new strategy to grow nonfouling poly (poly(ethylene glycol) methacrylate) (PPEGMA) brushes from polydimethylsiloxane (PDMS) substrates. The strategy presented here is based on the use of a sequence of vapor deposition/hydrolysi ...

2009

The term polymer brush refers to a well defined arrangement of polymer chains, which are tethered with one end to an interface and usually the surface of a solid substrate. Due to steric repulsion the polymer chains furthermore adopt a defined, stretched c ...

EPFL2007

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This manuscript describes the synthesis of poly(methacrylic acid) (PMAA) brushes via surface-initiated atom transfer radical polymerization (SI-ATRP) of sodium methacrylate (NaMA) and their use as substrates for the mineralization of calcium carbonate. A C ...

2007

RGD-Functionalized polymer brushes as substrates for the integrin specific adhesion of human umbilical vein endothelial cells

Nikolaos Stergiopoulos, Harm-Anton Klok, Paolo Silacci, Stefano Tugulu

This report demonstrates the feasibility of surface-initiated atom transfer radical polymerization to prepare thin polymer layers ("brushes") that can be functionalized with short peptide ligands and which may be of use as coatings to promote endothelializ ...

2007

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Protein microarrays are an attractive approach for the high-throughput analysis of protein function, but their impact on proteomics has been limited by the technical difficulties associated with their generation. Here we demonstrate that fusion proteins of ...

2006

Polymer brushes as ionotropic matrices for the directed fabrication of microstructured calcite thin films

Harm-Anton Klok, Stefano Tugulu

(Figure Presented) How to get into films: Micropatterned poly(methacrylic acid) (PMAA) brushes are used as an ionotropic matrix for the fabrication of microstructured calcite thin films. The calcite films are an exact 3D replica of the PMAA brush matrix (s ...

2006

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Understanding and controlling the interactions between synthetic and biol. materials is of great importance for the development of novel materials for a variety of biomedical and bioanal. applications, including for example stents, vascular grafts and prot ...

2005

A novel star PEG-derived surface coating for specific cell adhesion

Harm-Anton Klok, Stefano Tugulu

In this study a novel approach for the coating and functionalization of substrates for cell culture and tissue engineering is presented. Glass, silicon, and titanium panes were coated with an ultrathin film (30 ± 5 nm) of reactive star-shaped poly(ethylene ...

2005

Protein-Functionalized Polymer Brushes

Harm-Anton Klok, Kai Johnsson, Stefano Tugulu, India Christina Sielaff, Anke Arnold

A new strategy for the prepn. of protein-functionalized polymer brushes is reported, which is based on a combination of surface-initiated atom transfer radical polymn. (ATRP), p-nitrophenyl chloroformate activation of the surface hydroxyl groups, and subse ...

2005