Publications de Tanja Cloé Hausherr

Effect of temporal onsets of mechanical loading on bone formation inside a tissue engineering scaffold combined with cell therapy

Several approaches to combine bone substitutes with biomolecules, cells or mechanical loading have been explored as an alternative to the limitation and risk-related bone auto- and allo-grafts. In particular, human bone progenitor cells seeded in porous po ...

2018

Human bone progenitor cells for clinical application: what kind of immune reaction does fetal xenograft tissue trigger in immuno-competent rats?

Dominique Pioletti, Lee Ann Laurent-Applegate, Tanja Cloé Hausherr

The potential of human fetal bone cells for successful bone regeneration has been shown in vivo. In particular, it has been demonstrated that the seeding of these cells in porous poly-(L-lactic acid)/ ß-tricalcium phosphate scaffolds improved the bone form ...

Cognizant Communication Corp2017

In vivo mechanical loading combined with cell therapy in a bone tissue engineering scaffold

Tanja Cloé Hausherr

Bone defects generate a worldwide high demand for bone repair and reconstruction. The incidence of bone defect repair in our aging society is expected to increase in the next decades. As bone auto- and allografting solutions often suffer from limited suppl ...

EPFL2016

Microfluidic Synthesis of Cell-Type-Specific Artificial Extracellular Matrix Hydrogels

Matthias Lütolf, Tanja Cloé Hausherr, Simone Allazetta

Droplet microfluidic technology is applied for the high-throughput synthesis via Michael-type addition of reactive, micrometer-sized poly(ethylene glycol) (PEG) hydrogels (“microgels”) with precisely controlled dimension and physicochemical properties. A v ...

American Chemical Society2013

Capillary-valve-based platform towards cell-on-chip mechanotransduction assays

Martinus Gijs, Dominique Pioletti, Hicham Majd, Christophe Yamahata, Tanja Cloé Hausherr, Arnaud Müller

Reliable in vitro models are required to understand the ability of cells to respond and adapt to mechanical stimuli. To mimic and interface with the microenvironment, lab-on-a-chip devices and microelectromechanical systems (MEMS) provide excellent options ...

Elsevier2013