Publications de Benjamin Zoller

Modulation of transcriptional burst frequency by histone acetylation

Felix Naef, David Michael Suter, Benjamin Zoller, Damien Lionel Nicolas

National Academy of Sciences2018

CAST: An automated segmentation and tracking tool for the analysis of transcriptional kinetics from single-cell time-lapse recordings

Felix Naef, Benjamin Zoller, Damien Lionel Nicolas, Simon Blanchoud, Onur Tidin

Fluorescence and bioluminescence time-lapse imaging allows to investigate a vast range of cellular processes at single-cell or even subcellular resolution. In particular, time-lapse imaging can provide uniquely detailed information on the fine kinetics of ...

Academic Press Inc Elsevier Science2015

Modeling of transcription mechanisms in mammals from kinetic measurements in single cells

Benjamin Zoller

In mammals, transcription was observed to occur predominantly in bursts, resulting from short and intense periods of gene transcription interspersed by longer silent periods. In order to elucidate the causes and the consequences of discontinuous transcript ...

EPFL2014

Stimulus-induced modulation of transcriptional bursting in a single mammalian gene

Felix Naef, Benjamin Zoller, David Michael Suter, Rosamaria Cannavo

Mammalian genes are often transcribed discontinuously as short bursts of RNA synthesis followed by longer silent periods. However, how these "on" and "off" transitions, together with the burst sizes, are modulated in single cells to increase gene expressio ...

National Academy of Sciences2013