Peter Frey

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Publications associées (42)

In-vivo performance of high-density collagen gel tubes for urethral regeneration in a rabbit model

Jeffrey Alan Hubbell, Peter Frey, Lionel Ambroise Micol

Congenital malformations or injuries of the urethra can be treated using existing autologous tissue, but these procedures are sometimes associated with severe complications. Therefore, tissue engineering may be advantageous for generating urethral grafts. ...

Elsevier2012

Single cell analysis of porcine and human urothelial cells

Yann Barrandon, Jeffrey Alan Hubbell, Peter Frey, Hans Mattias Larsson, François Gorostidi

Wiley-Blackwell2012

Compressed fibrin-collagen scaffolds for enhancing bladder tissue regeneration: a bioreactor cell culture system

Jeffrey Alan Hubbell, Peter Frey, Elif Vardar, Eva-Maria Balet

Wiley-Blackwell2012

Sorting Live Stem Cells Based on Sox2 mRNA Expression

Matthias Lütolf, Peter Frey, Jeffrey Alan Hubbell, Hans Mattias Larsson, Seung Tae Lee

While cell sorting usually relies on cell-surface protein markers, molecular beacons (MBs) offer the potential to sort cells based on the presence of any expressed mRNA and in principle could be extremely useful to sort rare cell populations from primary i ...

Public Library of Science2012

A collagen-poly(lactic acid-co-epsilon-caprolactone) hybrid scaffold for bladder tissue regeneration

Florian Maria Wurm, Peter Frey, Jeffrey Alan Hubbell, Lionel Ambroise Micol

Scaffold materials should favor cell attachment and proliferation, and provide designable 3D structures with appropriate mechanical strength. Collagen matrices have proven to be beneficial scaffolds for tissue regeneration. However, apart from small intest ...

2011

High-density collagen gel tubes as a matrix for primary human bladder smooth muscle cells

Jeffrey Alan Hubbell, Peter Frey, Lionel Ambroise Micol

Tissue-engineered grafts for the urinary tract are being investigated for the potential treatment of several urologic diseases. These grafts, predominantly tubular-shaped, usually require in vitro culture prior to implantation to allow cell engraftment on ...

Elsevier2011

Tg-aprotinin fusion proteins and matrices thereof

Jeffrey Alan Hubbell, Peter Frey, Kristen Lorentz

Fusion proteins containing a first domain and a second domain, where the first domain contains a crosslinkable substrate domain and the second domain contains a fibrinolysis inhibitor, are provided. In a preferred embodiment, the fibrinolysis inhibitor is ...

2011

Engineered aprotinin for improved stability of fibrin biomaterials

Jeffrey Alan Hubbell, Peter Frey, Stephane Kontos, Kristen Lorentz

Fibrin has been long used clinically for hemostasis and sealing, yet extension of use in other applications has been limited due to its relatively rapid resorption in vivo, even with addition of aprotinin or other protease inhibitors. We report an engineer ...

2011

Compressed collagen gel: a novel scaffold for human bladder cells

Florian Maria Wurm, Jeffrey Alan Hubbell, Peter Frey

Collagen is highly conserved across species and has been used extensively for tissue regeneration; however, its mechanical properties are limited. A recent advance using plastic compression of collagen gels to achieve much higher concentrations significant ...

Wiley-Blackwell2010

In vivo study of an injectable poly(acrylonitrile)-based hydrogel paste as a bulking agent for the treatment of urinary incontinence

Jeffrey Alan Hubbell, Peter Frey, Lionel Ambroise Micol

Urinary incontinence can be treated by endoscopic injection of bulking agents, however, no optimal therapeutic effect has been achieved upon this treatment yet. In the present study, the development of a injectable poly(acrylonitrile) hydrogel paste is des ...

Elsevier2010

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In vivo study of an injectable poly(acrylonitrile)-based hydrogel paste as a bulking agent for the treatment of urinary incontinence

Jeffrey Alan Hubbell, Peter Frey, Lionel Ambroise Micol

Elsevier2010

Compressed fibrin-collagen scaffolds for enhancing bladder tissue regeneration: a bioreactor cell culture system

Jeffrey Alan Hubbell, Peter Frey, Elif Vardar, Eva-Maria Balet

Wiley-Blackwell2012

Tg-aprotinin fusion proteins and matrices thereof

Jeffrey Alan Hubbell, Peter Frey, Kristen Lorentz

2011