Priscilla Turelli

Publications associées (38)

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The KRAB-ZFP/KAP1 System Contributes to the Early Embryonic Establishment of Site-Specific DNA Methylation Patterns Maintained during Development

Didier Trono, Priscilla Turelli, Sandra Eloise Kjeldsen, Adamantia Kapopoulou, Karolina Bojkowska, Charlène Mireille Raymonde Raclot

De novo DNA methylation is an essential aspect of the epigenetic reprogramming that takes place during early development, yet factors responsible for its instatement at particular genomic loci are poorly defined. Here, we demonstrate that the KRAB-ZFP-medi ...

Elsevier2012

Functional analysis and structural modeling of human APOBEC3G reveal the role of evolutionarily conserved elements in the inhibition of human immunodeficiency virus type 1 infection and Alu transposition

Didier Trono, Priscilla Turelli, Olivier Michielin, Bastien Mangeat

Retroelements are important evolutionary forces but can be deleterious if left uncontrolled. Members of the human APOBEC3 family of cytidine deaminases can inhibit a wide range of endogenous, as well as exogenous, retroelements. These enzymes are structura ...

American Society for Microbiology2009

APOBEC3-independent interferon-induced viral clearance in hepatitis B virus transgenic mice

Didier Trono, Priscilla Turelli, Bastien Mangeat, Stéphanie Jost, Sonia Verp

Interferon (IFN) has been part of the standard treatment of chronic hepatitis B infection for more than 2 decades, yet the mechanism of action of this antiviral remains poorly understood. It was recently observed that members of the human APOBEC family of ...

American Society for Microbiology2008

Induction of antiviral cytidine deaminases does not explain the inhibition of hepatitis B virus replication by interferons

Didier Trono, Priscilla Turelli, Stéphanie Jost, Bastien Mangeat

American Society for Microbiology2007

Interfering residues narrow the spectrum of MLV restriction by human TRIM5alpha

Didier Trono, Priscilla Turelli, Séverine Reynard, Pierre Maillard

TRIM5alpha is a restriction factor that limits infection of human cells by so-called N- but not B- or NB-tropic strains of murine leukemia virus (MLV). Here, we performed a mutation-based functional analysis of TRIM5alpha-mediated MLV restriction. Our resu ...

Public Library of Science2007

The integrase interactor 1 (INI1) proteins facilitate Tat-mediated human immunodeficiency virus type 1 transcription

Didier Trono, Priscilla Turelli, Amalio Telenti

2006

DNA damage sensors ATM, ATR, DNA-PKcs, and PARP-1 are dispensable for human immunodeficiency virus type 1 integration

Didier Trono, Priscilla Turelli

Integration of a DNA copy of the viral RNA genome is a crucial step in the life cycle of human immunodeficiency virus type 1 (HIV-1) and other retroviruses. While the virally encoded integrase is key to this process, cellular factors yet to be characterize ...

American Society for Microbiology2005

Editing at the crossroad of innate and adaptive immunity