Publications de Aurélie Quintin

Plasticity of fetal cartilaginous cells

Dominique Pioletti, Corinne Scaletta, Lee Ann Laurent-Applegate, Sandra Jaccoud, Aurélie Quintin

Tissue-specific stem cells found in adult tissues can participate to the repair process following injury. However adult tissues, such as articular cartilage and intervertebral disc, have low regeneration capacity, whereas fetal tissues, such as articular c ...

2010

Fetal cells for intervertebral disc regeneration

Aurélie Quintin

Degeneration of the intervertebral disc (IVD) is thought to be one main factor in the development of back pain. It is not a symptom by itself but can lead to painful pathological conditions. Current treatments aim at relieving pain by conservative care, me ...

EPFL2009

Isolation and in vitro chondrogenic potential of human fetal spine cells

Dominique Pioletti, Corinne Scaletta, Lee Ann Laurent-Applegate, Sandra Jaccoud, Aurélie Quintin

Cell therapy for nucleus pulposus regeneration is an attractive treatment for early disc degeneration as shown by studies using autologous nucleus pulposus cells or stem cells. Another potential source of cells is fetal cells. We investigated the feasibili ...

2009

Consistency of fetal cell banks for research and clinical use

Dominique Pioletti, Corinne Scaletta, Lee Ann Laurent-Applegate, Aurélie Quintin

Current restrictions for human cell-based therapies have been related to technological limitations with regards to cellular proliferation capacity and maintenance of differentiated phenotype for primary human cell culture. In our experience, we have seen t ...

2007