Publications de Michele Giugliano

Markov Models of Ion Channels

Springer Science+Business Media2022

Locomotion modulates specific functional cell types in the mouse visual thalamus

The visual system is composed of diverse cell types that encode distinct aspects of the visual scene and may form separate processing channels. Here we present further evidence for that hypothesis whereby functional cell groups in the dorsal lateral genicu ...

Springer Nature2018

Dynamical response properties of neocortical neurons to conductance-driven time-varying inputs

Michele Giugliano

2018

Human Pluripotent Stem-Cell-Derived Cortical Neurons Integrate Functionally into the Lesioned Adult Murine Visual Cortex in an Area-Specific Way

Michele Giugliano

2018

Single-layer graphene modulates neuronal communication and augments membrane ion currents

Michele Giugliano

2018

Diamond microelectrode arrays for in vitro neuronal recordings

Michele Giugliano

A novel microfabrication technique for microelectrode arrays (MEAs) with a full diamond-cell interface is demonstrated. Boron-doped nano-crystalline diamond (BNCD) is used as a conductive electrode material on metal tracks insulated by intrinsic NCD. MEAs ...

Cambridge Univ Press2017

All-diamond functional surface micro-electrode arrays for brain-slice neural analysis

Ladislav Kavan, Michele Giugliano

Diamond-based microelectrode arrays were fabricated by using nanocrystalline diamond as an insulating layer and conductive boron-doped in order to used them for analysis of brain cortical slices. MEA surface is solely composed of diamond, exposed to the ce ...

Wiley-VCH Verlag2017

Brief wide-field photostimuli evoke and modulate oscillatory reverberating activity in cortical networks

Michele Giugliano

Cell assemblies manipulation by optogenetics is pivotal to advance neuroscience and neuroengineering. In in vivo applications, photostimulation often broadly addresses a population of cells simultaneously, leading to feed-forward and to reverberating respo ...

Nature Research2016

The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A

Michele Giugliano

Neuronal function is highly sensitive to changes in oxygen levels, but how hypoxia affects dendritic spine formation and synaptogenesis is unknown. Here we report that hypoxia, chemical inhibition of the oxygen-sensing prolyl hydroxylase domain proteins (P ...

Elsevier2016

On the Firing Rate Dependency of the Phase Response Curve of Rat Purkinje Neurons In Vitro

Michele Giugliano

Synchronous spiking during cerebellar tasks has been observed across Purkinje cells: however, little is known about the intrinsic cellular mechanisms responsible for its initiation, cessation and stability. The Phase Response Curve (PRC), a simple input-ou ...

Public Library Science2015